| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000646516 |
| Family | AA5 |
| Protein Properties | Length: 537 Molecular Weight: 58779.1 Isoelectric Point: 8.2527 |
| Chromosome | Chromosome/Scaffold: 003162287 Start: 11061 End: 12671 |
| Description | glyoxal oxidase-related protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA5 | 25 | 535 | 0 |
| AAGGKWQVLKNVGISAMHMQLFKNDRIVMFDRTDFGKSNLSLANGNCVNNDCTAHSAEFVVQTNALRPLTVLSDVWCSSGSMDAYGNLIQTGGFNSGERR VRVFTPCTGCDWKETVDGLAVRRWYATNHMLPDGREIIIGGRGQFNYEFSPKTESTSNVYSLPFLSQTNDPGQENNLYPFVFLNPDGNLFIFANNRAILL DYVKNAVVKTYPQIPGGDPRSYPSTGSAVLLPLKNLTAPAVEAEVLVCGGAPKGSFSQANKGVFVEALNTCARIKITDPNPQWIVETMPQARVMGDMILL PDSTVLIINGASSGAAGWEIGRNPVLNPVVYQPDNAIGSRFEQQNPTTIPRMYHSSALLVRDGRVIVGGSNPHDKYQFGSNVLFPTELRLEAFSPEYLDA KYADLRPTIIAPRNQAKIRYGRKLTVQFSLAGRFAMNSVSVTMVAPPFSTHSFSMNQRLLVLGAENTHQVGPTTYEAQVTTPPSGNLAPSGYYILYVVHQ QIPSEGIFVKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 537 Download |
| MKTISLIDLS LLLLTFNFSV LTAHAAGGKW QVLKNVGISA MHMQLFKNDR IVMFDRTDFG 60 KSNLSLANGN CVNNDCTAHS AEFVVQTNAL RPLTVLSDVW CSSGSMDAYG NLIQTGGFNS 120 GERRVRVFTP CTGCDWKETV DGLAVRRWYA TNHMLPDGRE IIIGGRGQFN YEFSPKTEST 180 SNVYSLPFLS QTNDPGQENN LYPFVFLNPD GNLFIFANNR AILLDYVKNA VVKTYPQIPG 240 GDPRSYPSTG SAVLLPLKNL TAPAVEAEVL VCGGAPKGSF SQANKGVFVE ALNTCARIKI 300 TDPNPQWIVE TMPQARVMGD MILLPDSTVL IINGASSGAA GWEIGRNPVL NPVVYQPDNA 360 IGSRFEQQNP TTIPRMYHSS ALLVRDGRVI VGGSNPHDKY QFGSNVLFPT ELRLEAFSPE 420 YLDAKYADLR PTIIAPRNQA KIRYGRKLTV QFSLAGRFAM NSVSVTMVAP PFSTHSFSMN 480 QRLLVLGAEN THQVGPTTYE AQVTTPPSGN LAPSGYYILY VVHQQIPSEG IFVKIY* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam09118 | DUF1929 | 4.0e-24 | 430 | 535 | 107 | + Domain of unknown function (DUF1929). Members of this family adopt a secondary structure consisting of a bundle of seven, mostly antiparallel, beta-strands surrounding a hydrophobic core. The 7 strands are arranged in 2 sheets, in a Greek-key topology. Their precise function, has not, as yet, been defined, though they are mostly found in sugar-utilising enzymes, such as galactose oxidase. | ||
| cd02851 | E_set_GO_C | 2.0e-26 | 426 | 535 | 111 | + C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others. | ||
| pfam07250 | Glyoxal_oxid_N | 2.0e-124 | 41 | 274 | 245 | + Glyoxal oxidase N-terminus. This family represents the N-terminus (approximately 300 residues) of a number of plant and fungal glyoxal oxidase enzymes. Glyoxal oxidase catalyzes the oxidation of aldehydes to carboxylic acids, coupled with reduction of dioxygen to hydrogen peroxide. It is an essential component of the extracellular lignin degradation pathways of the wood-rot fungus Phanerochaete chrysosporium. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_173419.1 | 0 | 23 | 535 | 26 | 547 | glyoxal oxidase-related [Arabidopsis thaliana] |
| RefSeq | NP_177692.1 | 0 | 18 | 535 | 22 | 546 | glyoxal oxidase-related [Arabidopsis thaliana] |
| RefSeq | XP_002280559.1 | 0 | 20 | 535 | 31 | 552 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002301997.1 | 0 | 25 | 535 | 2 | 523 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510488.1 | 0 | 24 | 535 | 27 | 546 | Galactose oxidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2eid_A | 2e-18 | 91 | 535 | 217 | 637 | A Chain A, Galactose Oxidase W290g Mutant |
| PDB | 2wq8_A | 4e-18 | 91 | 535 | 239 | 659 | A Chain A, Glycan Labelling Using Engineered Variants Of Galactose Oxidase Obtained By Directed Evolution |
| PDB | 1t2x_A | 5e-18 | 91 | 535 | 217 | 637 | A Chain A, Glactose Oxidase C383s Mutant Identified By Directed Evolution |
| PDB | 2eic_A | 5e-18 | 91 | 535 | 217 | 637 | A Chain A, Crystal Structure Of Galactose Oxidase Mutant W290f |
| PDB | 1k3i_A | 6e-18 | 91 | 535 | 234 | 654 | A Chain A, Crystal Structure Of The Precursor Of Galactose Oxidase |
