Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000669665 |
Family | GT47 |
Protein Properties | Length: 666 Molecular Weight: 75569 Isoelectric Point: 5.7029 |
Chromosome | Chromosome/Scaffold: 020509125 Start: 2933 End: 4930 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 204 | 543 | 0 |
GKYIYVHDLPSRFNEDMLKECRSLSLWTNMCKFTTNAGLGPPLENAEGVFGDTSWYATNQFAVDVIFNNRMKQYECLTNDSSIAAAIFVPFYAGFDIARY LWGFNISRRDAASLDLVDWLMKRPEWGIMGGKDHFLVAGRITWDFRRLSEEESDWGNKLLFLPAAKNMSMLVVESSPWNANDFGIPYPTYFHPAKDADVF VWQERMRRLKREFLFSFAGAPRPDNXKSIRGQIIDQCRSSKVGKLLECDFGESKCHSPSSIMQMFQRSLFCLQPQGDSYTRRSAFDSMLAGCIPVFFHPG SAYTQYTWHLPKDYTRYSVFIPEDDIRKRNVSIEETLGRI |
Full Sequence |
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Protein Sequence Length: 666 Download |
MNSLRRRSPD SVPVEPMEKG TGKNQNTRIY FLACLSVFFW MLLLYFHFVV LGGGTVNESV 60 NIQAGPVYSE VKPTLVTNDL QMDSKSTVST PTPVARYHQK DNQNTESTPT GVTVDLQMDN 120 QNTEATPTYT DDHQMDNKNT EAAPNSVTGD QQMGNQSTGS TPTNVAIAQQ TEAPAKTDQI 180 NEVEKYPFMR ALGTAENKSD PCGGKYIYVH DLPSRFNEDM LKECRSLSLW TNMCKFTTNA 240 GLGPPLENAE GVFGDTSWYA TNQFAVDVIF NNRMKQYECL TNDSSIAAAI FVPFYAGFDI 300 ARYLWGFNIS RRDAASLDLV DWLMKRPEWG IMGGKDHFLV AGRITWDFRR LSEEESDWGN 360 KLLFLPAAKN MSMLVVESSP WNANDFGIPY PTYFHPAKDA DVFVWQERMR RLKREFLFSF 420 AGAPRPDNXK SIRGQIIDQC RSSKVGKLLE CDFGESKCHS PSSIMQMFQR SLFCLQPQGD 480 SYTRRSAFDS MLAGCIPVFF HPGSAYTQYT WHLPKDYTRY SVFIPEDDIR KRNVSIEETL 540 GRIPPEQVKK MREEVINLIP SMIYADPRSK LRIFRDAFDV XVQAIIDKVT NLRKDIIEGR 600 IDDNFIEENS WKYALLEEGQ RXVGAHEWDP FFSKPKDGNG DSVDASAEAA KNSWHNEXRH 660 QSSGR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-71 | 201 | 543 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACY08857.1 | 0 | 4 | 662 | 1 | 617 | xyloglucan galactosyltransferase [Eucalyptus grandis] |
DDBJ | BAE98519.1 | 0 | 162 | 662 | 111 | 618 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | XP_002269766.1 | 0 | 2 | 642 | 57 | 648 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002301846.1 | 0 | 126 | 662 | 57 | 585 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |