Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000693745 |
Family | GT47 |
Protein Properties | Length: 561 Molecular Weight: 63347.8 Isoelectric Point: 10.0134 |
Chromosome | Chromosome/Scaffold: 00547952 Start: 1899 End: 7949 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 170 | 488 | 0 |
LLRVFMYELPPEFHFGLLGWKGKENQTWPNVKNLSLIPAYPGGLNLQHSIEYWLTLDLLSSSIPTVVRPCTVVRVHNSSQADVIFVPFFASLXYNRHSKL RGNEEVSVNKKLQGKLVQYLMGRDEWKRKGGKDHLLVAHHPNSMLDARKKLGSAMFVLADFGRYSAEIANLEKDIIAPYRHLVMTVQSSKSPSFNERPIL LYFRGAIYRKDGGMVRKKLXYLLKDEKDVNFTFGSVQGXGINKASQGMASSKFCLNLAGDTPSSNRLFDAIASHCVPVIISDEIELPFEDVLDYSQFCIF VRSSYACKKGYLLNLLRGI |
Full Sequence |
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Protein Sequence Length: 561 Download |
MAMAKLVCFL LLALLGISMA ATQVMAKEQA RNQLDSGGYG PGSLKSYQCP SQCTRRCSQT 60 QYHKPCMFFC QKCCAKCLCV PPGFYGNKAF SNTSFAPAVF KLVVLNGTYF EPLVKSRDKN 120 LPSFSSEVPR VDAKGSTKRC ELGCQVSNSS KKLGFLEKKK MVACDSTQAL LRVFMYELPP 180 EFHFGLLGWK GKENQTWPNV KNLSLIPAYP GGLNLQHSIE YWLTLDLLSS SIPTVVRPCT 240 VVRVHNSSQA DVIFVPFFAS LXYNRHSKLR GNEEVSVNKK LQGKLVQYLM GRDEWKRKGG 300 KDHLLVAHHP NSMLDARKKL GSAMFVLADF GRYSAEIANL EKDIIAPYRH LVMTVQSSKS 360 PSFNERPILL YFRGAIYRKD GGMVRKKLXY LLKDEKDVNF TFGSVQGXGI NKASQGMASS 420 KFCLNLAGDT PSSNRLFDAI ASHCVPVIIS DEIELPFEDV LDYSQFCIFV RSSYACKKGY 480 LLNLLRGIKQ ETWTKMWERL KEVVHHFGYQ YPSQPGDAVD MIWQAVSHKK SSTQFKFHSR 540 QFKFHRKKRY DRSTSGIRTK * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam02704 | GASA | 4.0e-22 | 48 | 88 | 41 | + Gibberellin regulated protein. This is the GASA gibberellin regulated cysteine rich protein family. The expression of these proteins is up-regulated by the plant hormone gibberellin, most of these proteins have some role in plant development. There are 12 cysteine residues conserved within the alignment giving the potential for these proteins to posses 6 disulphide bonds. | ||
pfam03016 | Exostosin | 1.0e-50 | 171 | 488 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_565089.1 | 0 | 150 | 555 | 58 | 460 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 90 | 553 | 33 | 448 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 141 | 553 | 4 | 409 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 171 | 552 | 3 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 91 | 552 | 34 | 486 | catalytic, putative [Ricinus communis] |