y
Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000727481 |
Family | AA3 |
Protein Properties | Length: 292 Molecular Weight: 31648.3 Isoelectric Point: 5.6018 |
Chromosome | Chromosome/Scaffold: 018343157 Start: 365 End: 2309 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 1 | 284 | 2.5e-34 |
MLSGVGPAEQLKAHNITVVVDQPMVGQGMSDNPMNAIFVPSPIPVEVSLIQVVGITHFGSYIEAASGENFAGGSTTKDFGMFSPKIGQLSTVPPKQRTPE ALAEAVRYMDSLEDAAFXGGFILEKVMGPISTGHMELRTRNPNDNPAVTFNYFKEPQDLERCVQGIETIEKIXESKAFSKFRYEGMSIAALLNATASSPV NLLPKHANASRSLDQFCKDXVMTIWHYHGGCQVGRVVDHDYKVLGVDALRVIDGSTFNYSPGTNPQATVMMLGRYMGKTILDER |
Full Sequence |
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Protein Sequence Length: 292 Download |
MLSGVGPAEQ LKAHNITVVV DQPMVGQGMS DNPMNAIFVP SPIPVEVSLI QVVGITHFGS 60 YIEAASGENF AGGSTTKDFG MFSPKIGQLS TVPPKQRTPE ALAEAVRYMD SLEDAAFXGG 120 FILEKVMGPI STGHMELRTR NPNDNPAVTF NYFKEPQDLE RCVQGIETIE KIXESKAFSK 180 FRYEGMSIAA LLNATASSPV NLLPKHANAS RSLDQFCKDX VMTIWHYHGG CQVGRVVDHD 240 YKVLGVDALR VIDGSTFNYS PGTNPQATVM MLGRYMGKTI LDERLASDVS N* 300 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 1.0e-15 | 127 | 273 | 151 | + choline dehydrogenase; Validated | ||
TIGR01810 | betA | 1.0e-19 | 1 | 281 | 298 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 4.0e-22 | 1 | 287 | 296 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
pfam05199 | GMC_oxred_C | 2.0e-25 | 129 | 273 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
PLN02785 | PLN02785 | 1.0e-137 | 1 | 285 | 286 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 1 | 290 | 288 | 577 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_001053612.1 | 0 | 1 | 288 | 290 | 584 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002282510.1 | 0 | 1 | 290 | 254 | 543 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002298074.1 | 0 | 1 | 291 | 287 | 577 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002446965.1 | 0 | 1 | 288 | 293 | 588 | hypothetical protein SORBIDRAFT_06g025960 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ju2_B | 0 | 1 | 289 | 267 | 522 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 1ju2_A | 0 | 1 | 289 | 267 | 522 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_B | 0 | 1 | 288 | 267 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_A | 0 | 1 | 288 | 267 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdn_B | 0 | 1 | 288 | 267 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CX672181 | 276 | 7 | 281 | 0 |
HO799688 | 291 | 1 | 291 | 0 |
FQ439655 | 278 | 9 | 286 | 0 |
DY951927 | 276 | 9 | 284 | 0 |
FQ428027 | 265 | 9 | 273 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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