Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000839295 |
Family | GT47 |
Protein Properties | Length: 488 Molecular Weight: 55728.3 Isoelectric Point: 6.8239 |
Chromosome | Chromosome/Scaffold: 01591693 Start: 2162 End: 3625 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 60 | 404 | 0 |
SCSDRYIYIHDSLPARFNDDFINNCESLSAGTSMTNVPNMCPHLVNLGLGPKINNSDGVLSNAGWFVTNPYLLEVIFHNRMKKYECLTRNSTLASAIYVP FYPSMDVGVHLWDSNIEIRDSSAKEFVKWLSGQPEWTKMWGRDHFFASGRISWDFRRERDNSSNWGSKLRFLPESLNMTMLSIEGSRWKNDVAIPYPTNF HPSNDSEVVQWQDKVRKEERPYLFTFAGAPRPNQEGSIRGKLIEHCQASTNCNFLHCTEKICGNPITVMRAFQSSVYCLQPAGDSFTRRSTFDAFLAGCI PVFFHPATAYTQYLWYLPKNHTKYSVYIPVRDVTDLKEGSIEKIL |
Full Sequence |
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Protein Sequence Length: 488 Download |
MEKVHTGKCP QEVWFGILIS FALCFVLFSF DHSTSLSVDV LVNEKENPIR VLNFSHTKDS 60 CSDRYIYIHD SLPARFNDDF INNCESLSAG TSMTNVPNMC PHLVNLGLGP KINNSDGVLS 120 NAGWFVTNPY LLEVIFHNRM KKYECLTRNS TLASAIYVPF YPSMDVGVHL WDSNIEIRDS 180 SAKEFVKWLS GQPEWTKMWG RDHFFASGRI SWDFRRERDN SSNWGSKLRF LPESLNMTML 240 SIEGSRWKND VAIPYPTNFH PSNDSEVVQW QDKVRKEERP YLFTFAGAPR PNQEGSIRGK 300 LIEHCQASTN CNFLHCTEKI CGNPITVMRA FQSSVYCLQP AGDSFTRRST FDAFLAGCIP 360 VFFHPATAYT QYLWYLPKNH TKYSVYIPVR DVTDLKEGSI EKILLGISKD RELAMREEVI 420 RLIPKLVYAD PSSRLETKDA FDIAVQGILE RIENVRKEIR EGRDPSIGFA DEDNGKVTFP 480 KTIESLN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-62 | 108 | 397 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193135.2 | 0 | 13 | 479 | 31 | 511 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 59 | 482 | 91 | 510 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300146.1 | 0 | 9 | 479 | 16 | 512 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 26 | 477 | 21 | 463 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532518.1 | 0 | 9 | 487 | 10 | 529 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |