Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000840668 |
Family | GT47 |
Protein Properties | Length: 426 Molecular Weight: 48146.9 Isoelectric Point: 6.7289 |
Chromosome | Chromosome/Scaffold: 001798197 Start: 2264 End: 4111 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 58 | 353 | 0 |
RLKVFVYELPSKYNKKILQKDPRCLNHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRMMRSAXQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGILRMLQRATLVQTFGQKNHVCLKEGSITVPPYAPPQKMQTHLISEKTPRSIFVYFRGLFYDVGNDPEGGYYARGA RAAVWENFKDNPLFDISTEHPTTYYEDMQRAVFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEEIGVFVDEKDVPNLDTILTSI |
Full Sequence |
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Protein Sequence Length: 426 Download |
MLGCLAGVVA PRRRQMHNNA IVTMLMNSKD QELCGFDPFG FVGFGSAGDV LDDDPVGRLK 60 VFVYELPSKY NKKILQKDPR CLNHMFAAEI FMHRFLLSSP VRTLNPEEAD WFYTPVYTTC 120 DLTPNGLPLP FKSPRMMRSA XQLISSNWPY WNRTEGADHF FVVPHDFGAC FHYQEEKAIE 180 RGILRMLQRA TLVQTFGQKN HVCLKEGSIT VPPYAPPQKM QTHLISEKTP RSIFVYFRGL 240 FYDVGNDPEG GYYARGARAA VWENFKDNPL FDISTEHPTT YYEDMQRAVF CLCPLGWAPW 300 SPRLVEAVIF GCIPVIIADD IVLPFADAIP WEEIGVFVDE KDVPNLDTIL TSIPPELILR 360 KQRLLANPSM KQAMLFPQPA EAGDAFHQVL NGLARKLPHG PDXFLKPGXK ILNWTAGPVG 420 DLKPW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-82 | 58 | 353 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM64940.1 | 0 | 45 | 425 | 35 | 415 | unknown [Arabidopsis thaliana] |
RefSeq | NP_568941.1 | 0 | 45 | 425 | 35 | 415 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002284685.1 | 0 | 45 | 425 | 36 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318180.1 | 0 | 45 | 425 | 37 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 45 | 425 | 37 | 417 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GO868810 | 330 | 71 | 400 | 0 |
EX131890 | 308 | 60 | 367 | 0 |
ES900637 | 308 | 119 | 426 | 0 |
GO846508 | 325 | 102 | 426 | 0 |
GO868810 | 21 | 402 | 422 | 0.59 |
Sequence Alignments (This image is cropped. Click for full image.) |
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