Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000841470 |
Family | GH18 |
Protein Properties | Length: 256 Molecular Weight: 28115.5 Isoelectric Point: 7.2342 |
Chromosome | Chromosome/Scaffold: 018458226 Start: 20315 End: 21082 |
Description | chitinase A |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH18 | 44 | 203 | 4.8e-27 |
PEIKSCQAKGIKVILSRGGASGSYSLASADDARQVATDLWNNFLGGHSSSRPLGAAVLDGIDFDIEGGTDQHWDDLAKYLSGYSKRGKKVYLTAAPHCPF PDAWVGNALKTGLFDNVWVQFYNNPPCEYTPGNVDNLEIAWKQWTSAIPAHKIFLGLPAA |
Full Sequence |
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Protein Sequence Length: 256 Download |
MCFRELPICK PSFSHHIRHR PNPRHQPSRP VTVTQRPMNA PNCPEIKSCQ AKGIKVILSR 60 GGASGSYSLA SADDARQVAT DLWNNFLGGH SSSRPLGAAV LDGIDFDIEG GTDQHWDDLA 120 KYLSGYSKRG KKVYLTAAPH CPFPDAWVGN ALKTGLFDNV WVQFYNNPPC EYTPGNVDNL 180 EIAWKQWTSA IPAHKIFLGL PAAPQAAGSG XIPASDLNSQ VLPHMEXSCF GPSIMMILMD 240 EFMQFNTINF LGFYE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG3469 | COG3469 | 0.0001 | 102 | 213 | 143 | + Chitinase [Carbohydrate transport and metabolism] | ||
cd02871 | GH18_chitinase_D-like | 9.0e-9 | 45 | 221 | 213 | + GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus. | ||
pfam00704 | Glyco_hydro_18 | 2.0e-13 | 45 | 202 | 180 | + Glycosyl hydrolases family 18. | ||
cd02877 | GH18_hevamine_XipI_class_III | 3.0e-84 | 37 | 236 | 212 | + This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG25709.1 | 0 | 44 | 236 | 88 | 280 | AF309514_1 class III acidic chitinase [Malus x domestica] |
GenBank | ABF82271.1 | 0 | 45 | 236 | 88 | 279 | class III chitinase [Panax ginseng] |
RefSeq | XP_002279147.1 | 0 | 45 | 236 | 88 | 279 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002301383.1 | 0 | 45 | 236 | 88 | 279 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002320164.1 | 0 | 45 | 236 | 90 | 281 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2hvm_A | 0 | 46 | 228 | 64 | 246 | A Chain A, Structural Study Of The Aquifex Aeolicus Ppx-Gppa Enzyme |
PDB | 1llo_A | 0 | 46 | 228 | 64 | 246 | A Chain A, Structural Study Of The Aquifex Aeolicus Ppx-Gppa Enzyme |
PDB | 1hvq_A | 0 | 46 | 228 | 64 | 246 | A Chain A, Crystal Structures Of Hevamine, A Plant Defence Protein With Chitinase And Lysozyme Activity, And Its Complex With An Inhibitor |
PDB | 1kr0_A | 0 | 46 | 228 | 64 | 246 | A Chain A, Hevamine Mutant D125aY183F IN COMPLEX WITH TETRA-Nag |
PDB | 1kr1_A | 0 | 46 | 228 | 64 | 246 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FQ316915 | 192 | 45 | 236 | 0 |
FQ317294 | 192 | 45 | 236 | 0 |
JK988873 | 192 | 45 | 236 | 0 |
FQ316723 | 192 | 45 | 236 | 0 |
FQ355903 | 178 | 45 | 222 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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