| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000857857 |
| Family | GH47 |
| Protein Properties | Length: 596 Molecular Weight: 67586.3 Isoelectric Point: 6.1073 |
| Chromosome | Chromosome/Scaffold: 021232383 Start: 2851 End: 8298 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH47 | 110 | 563 | 0 |
| AMIHAWSSYEKYAWGQDELQPQSKNGVNSFGGLGATLVDSLDTLYIMGLHEQFQKAREWVATSLDFDKDYEASVFETTIRVVGGLLSAYDLSEDKLFLDK AREIADRLLPAWDTPSGIPYNIINLAHGKPHNPSWTGGESILADSGTEQVEFIALSQRTGDPKYQQRAENVIVALNKTFPDDGLLPIYIDPERGRSGYST ITFGAMGDSFYEYLLKVWILGNKTSAVKPYSGYVVMVFKFVLMSKFLWNVGSRDMWEKSMKGLLSLIRRTTPSSFAYLCEKNGNTMTNKMDELACFAPGM LALGSSGYGPDESKQFLSLAEELAWTCYNFYQSTPTKLXGENYFFHDGQDLSVGTSWNILRPETIESLFYLWRLTGNKTYQEWGWNIFQAFEKNSRIESG YVGLKDVNTGDKDNMMQSFFLAETLKYLYLLFSPSSVISLDEWVFNTEAHPIKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 596 Download |
| MARVRSSSSS RLRYCNPAYY LKRPQRLALL LIAFVCVTLV VWDRQTLLKE HEEEVAKLNE 60 QLSHLKSLVE DSQNVQGDAA KKNTLKDRDG EKEVGLDPID IQRREKVKEA MIHAWSSYEK 120 YAWGQDELQP QSKNGVNSFG GLGATLVDSL DTLYIMGLHE QFQKAREWVA TSLDFDKDYE 180 ASVFETTIRV VGGLLSAYDL SEDKLFLDKA REIADRLLPA WDTPSGIPYN IINLAHGKPH 240 NPSWTGGESI LADSGTEQVE FIALSQRTGD PKYQQRAENV IVALNKTFPD DGLLPIYIDP 300 ERGRSGYSTI TFGAMGDSFY EYLLKVWILG NKTSAVKPYS GYVVMVFKFV LMSKFLWNVG 360 SRDMWEKSMK GLLSLIRRTT PSSFAYLCEK NGNTMTNKMD ELACFAPGML ALGSSGYGPD 420 ESKQFLSLAE ELAWTCYNFY QSTPTKLXGE NYFFHDGQDL SVGTSWNILR PETIESLFYL 480 WRLTGNKTYQ EWGWNIFQAF EKNSRIESGY VGLKDVNTGD KDNMMQSFFL AETLKYLYLL 540 FSPSSVISLD EWVFNTEAHP IKIMARHDAD TSGKANGNDR PKIRLRGRKE GRSRD* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01532 | Glyco_hydro_47 | 0 | 110 | 563 | 473 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| PTZ00470 | PTZ00470 | 0 | 100 | 563 | 475 | + glycoside hydrolase family 47 protein; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF16414.1 | 0 | 11 | 593 | 14 | 577 | AF126550_1 mannosyl-oligosaccharide 1,2-alpha-mannosidase [Glycine max] |
| EMBL | CBI18472.1 | 0 | 1 | 595 | 1 | 574 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_175570.1 | 0 | 1 | 592 | 1 | 556 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | NP_566675.1 | 0 | 1 | 592 | 1 | 568 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002310939.1 | 0 | 1 | 550 | 1 | 524 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 102 | 574 | 19 | 476 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 98 | 563 | 4 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 98 | 563 | 4 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 98 | 563 | 4 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 98 | 563 | 82 | 534 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
