| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000896660 |
| Family | AA5 |
| Protein Properties | Length: 537 Molecular Weight: 58808.6 Isoelectric Point: 8.4264 |
| Chromosome | Chromosome/Scaffold: 04405210 Start: 3583 End: 5193 |
| Description | glyoxal oxidase-related protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA5 | 26 | 535 | 0 |
| AGGKWQVLKNVGISAMHMQLFKNDRIVLFDRTDFGKSNLSLPNGNCVXNDCTAHSAEFVVQTNAVRPLTVLSDVWCSSGSMDAYGNLIQTGGNNIGERRV RVFTPCTGCDWKEIVDGLAARRWYATNHILPDGREIIIGGRGQFNYEFYPKTASTSNVYSLPFLSQTNDPGQENNLYPFVFLNPDGNLFVFANNRAILLD YVKNVVVKTYPQIPGGDPRSYPSTGSAVLLPLKNLMAPSVEAEVLVCGGAPKGSFVQANKGTFVEALNTCARIKITDPNAQWIVETMPQARVMGDMLLLX DSTVLLINGASSGVAGWEIGRNPVFNPVVYRPDNAVGSRFEQQNPTTIPRMYHSSALLVRDGRVIVGGSNPHDKYQFGSDVLFPTELRLEAFSPEYLDAK YANLRPTIIAPGNQAKIHYGIKLAVQFSLTGTFTKNSVSVTMVAPPFSTHSFSMNQRLLVLAAENVQQVGPTTYQVQVTTPPSKNLAPSGYYILYVVHQQ IPSEGIFVKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 537 Download |
| MKTISLIDLS LLLLIINFSV LXAHAAGGKW QVLKNVGISA MHMQLFKNDR IVLFDRTDFG 60 KSNLSLPNGN CVXNDCTAHS AEFVVQTNAV RPLTVLSDVW CSSGSMDAYG NLIQTGGNNI 120 GERRVRVFTP CTGCDWKEIV DGLAARRWYA TNHILPDGRE IIIGGRGQFN YEFYPKTAST 180 SNVYSLPFLS QTNDPGQENN LYPFVFLNPD GNLFVFANNR AILLDYVKNV VVKTYPQIPG 240 GDPRSYPSTG SAVLLPLKNL MAPSVEAEVL VCGGAPKGSF VQANKGTFVE ALNTCARIKI 300 TDPNAQWIVE TMPQARVMGD MLLLXDSTVL LINGASSGVA GWEIGRNPVF NPVVYRPDNA 360 VGSRFEQQNP TTIPRMYHSS ALLVRDGRVI VGGSNPHDKY QFGSDVLFPT ELRLEAFSPE 420 YLDAKYANLR PTIIAPGNQA KIHYGIKLAV QFSLTGTFTK NSVSVTMVAP PFSTHSFSMN 480 QRLLVLAAEN VQQVGPTTYQ VQVTTPPSKN LAPSGYYILY VVHQQIPSEG IFVKIY* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam09118 | DUF1929 | 1.0e-15 | 430 | 535 | 107 | + Domain of unknown function (DUF1929). Members of this family adopt a secondary structure consisting of a bundle of seven, mostly antiparallel, beta-strands surrounding a hydrophobic core. The 7 strands are arranged in 2 sheets, in a Greek-key topology. Their precise function, has not, as yet, been defined, though they are mostly found in sugar-utilising enzymes, such as galactose oxidase. | ||
| cd02851 | E_set_GO_C | 5.0e-19 | 426 | 535 | 111 | + C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others. | ||
| pfam07250 | Glyoxal_oxid_N | 4.0e-125 | 41 | 274 | 245 | + Glyoxal oxidase N-terminus. This family represents the N-terminus (approximately 300 residues) of a number of plant and fungal glyoxal oxidase enzymes. Glyoxal oxidase catalyzes the oxidation of aldehydes to carboxylic acids, coupled with reduction of dioxygen to hydrogen peroxide. It is an essential component of the extracellular lignin degradation pathways of the wood-rot fungus Phanerochaete chrysosporium. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_173419.1 | 0 | 23 | 535 | 26 | 547 | glyoxal oxidase-related [Arabidopsis thaliana] |
| RefSeq | NP_177692.1 | 0 | 8 | 535 | 12 | 546 | glyoxal oxidase-related [Arabidopsis thaliana] |
| RefSeq | XP_002280559.1 | 0 | 24 | 535 | 34 | 552 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002301997.1 | 0 | 25 | 535 | 2 | 523 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510488.1 | 0 | 24 | 535 | 27 | 546 | Galactose oxidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wq8_A | 2e-18 | 91 | 535 | 239 | 659 | A Chain A, Glycan Labelling Using Engineered Variants Of Galactose Oxidase Obtained By Directed Evolution |
| PDB | 2eid_A | 3e-18 | 91 | 535 | 217 | 637 | A Chain A, Galactose Oxidase W290g Mutant |
| PDB | 2eic_A | 3e-18 | 91 | 535 | 217 | 637 | A Chain A, Crystal Structure Of Galactose Oxidase Mutant W290f |
| PDB | 2vz3_A | 1e-17 | 91 | 535 | 217 | 637 | A Chain A, Crystal Structure Of Galactose Oxidase Mutant W290f |
| PDB | 2vz1_A | 1e-17 | 91 | 535 | 217 | 637 | A Chain A, Crystal Structure Of Galactose Oxidase Mutant W290f |
