Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000909996 |
Family | GT57 |
Protein Properties | Length: 497 Molecular Weight: 57162.5 Isoelectric Point: 9.2885 |
Chromosome | Chromosome/Scaffold: 012182200 Start: 1576 End: 3703 |
Description | ALG6, ALG8 glycosyltransferase family |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT57 | 43 | 474 | 0 |
GDFEAQRHWMEITLNVPIKDWYRNSTVNDLRYWGLDYPPLTAYQSYVHGLFLRFFSPESVGLFASRGHESYLGKLLMRWTVLSSDALVFFPAILYFVLVY YAGQNPNRRRSDIAWHIAIILLNPCLILIDHGHFQYNCISLGLTMGAISSVLSDKDLVACVLYSLALNHKQMSAYFAPAFFSHLLGKCLRRRYPLLEVLK LGIVVLGTFIVVWWPYVHSTEDFLGVLSRLAPFERGIFEDYVANFWCTTSVLVKWKRLFPTQSLKLISLGATVSTFLPSMIQQIWAPSKPGFLYGLLNAF SFYLYSFQVHEKSILLPLLPASLLAMEEPMLYTWMTLYALFSMFPLLHRDKLVLPYLALSALFILLNHVPNGRRATRDTSALRSSVTTVSVLCSVVLHVV YLSVHPPARCPFLFEALIMLVCFTQFVCLTLY |
Full Sequence |
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Protein Sequence Length: 497 Download |
MEKSSKKKGE SQLHSCPLHC FRCWFESRYR CILTLVRNPP KYGDFEAQRH WMEITLNVPI 60 KDWYRNSTVN DLRYWGLDYP PLTAYQSYVH GLFLRFFSPE SVGLFASRGH ESYLGKLLMR 120 WTVLSSDALV FFPAILYFVL VYYAGQNPNR RRSDIAWHIA IILLNPCLIL IDHGHFQYNC 180 ISLGLTMGAI SSVLSDKDLV ACVLYSLALN HKQMSAYFAP AFFSHLLGKC LRRRYPLLEV 240 LKLGIVVLGT FIVVWWPYVH STEDFLGVLS RLAPFERGIF EDYVANFWCT TSVLVKWKRL 300 FPTQSLKLIS LGATVSTFLP SMIQQIWAPS KPGFLYGLLN AFSFYLYSFQ VHEKSILLPL 360 LPASLLAMEE PMLYTWMTLY ALFSMFPLLH RDKLVLPYLA LSALFILLNH VPNGRRATRD 420 TSALRSSVTT VSVLCSVVLH VVYLSVHPPA RCPFLFEALI MLVCFTQFVC LTLYANAKQW 480 MLLKDFNLVD KEKKLL* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
COG5650 | COG5650 | 0.004 | 43 | 259 | 217 | + Predicted integral membrane protein [Function unknown] |
pfam03155 | Alg6_Alg8 | 2.0e-96 | 39 | 407 | 378 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. |
Gene Ontology | |
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GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_001145139.1 | 0 | 40 | 495 | 59 | 519 | hypothetical protein LOC100278369 [Zea mays] |
RefSeq | NP_198662.1 | 0 | 39 | 494 | 67 | 531 | ALG6, ALG8 glycosyltransferase family protein [Arabidopsis thaliana] |
RefSeq | XP_002280181.1 | 0 | 38 | 496 | 57 | 516 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002305159.1 | 0 | 38 | 495 | 28 | 490 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329281.1 | 0 | 38 | 495 | 24 | 485 | predicted protein [Populus trichocarpa] |