Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000913703 |
Family | GT20 |
Protein Properties | Length: 849 Molecular Weight: 95896.3 Isoelectric Point: 6.1958 |
Chromosome | Chromosome/Scaffold: 011437437 Start: 22394 End: 25714 |
Description | UDP-Glycosyltransferase / trehalose-phosphatase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 49 | 545 | 0 |
SSSQRDRIIIVANQLPIRAQRKADDSKGWIFSWDENSLLLQLKDGLGDDEIEVIYVGCLKEEIHPNEQDEVSQILLETFKCVPTFLPPDLFSRYYHGFCK QQLWPLFHYMLPLSPDLGGRFNRSLWQAYVSVNKIFADRIMEVINPEDDFVWVHDYHLMVLPTFLRKRFNRAKLGFFLHSPFPSSEIYKTLPVREEILRA LLNSDLIGFHTFDYARHFLSCCSRMLGLTYESKRGYIGLEYYGRTVSIKILPVGIHMGQLQSVLSLPETEAKVAELIKQFSDQGRTMLLGVDDMDIFKGI SLKLLAMEQLLVQHPEWQGKVVLVQIANPARGRGKDVKEVQAETSSTVKRINETFGRPGYKPVVLIDEPLKFYERIAYYVVAECCLVTAVRDGMNLIPYE YIIGRQGNSKLDKVLGLEPSIPKKSMLVVSEFIGCSPSLSGAIRVNPWNIDAVADAMDCALEMAEPEKQLRHEKHYRYVSTHDVGYWARSFLQDLER |
Full Sequence |
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Protein Sequence Length: 849 Download |
MVSKSYSNLL ELASGEGDSF GRIGRRIPRV MNVAGVMSDV DDEGYTSSSS SQRDRIIIVA 60 NQLPIRAQRK ADDSKGWIFS WDENSLLLQL KDGLGDDEIE VIYVGCLKEE IHPNEQDEVS 120 QILLETFKCV PTFLPPDLFS RYYHGFCKQQ LWPLFHYMLP LSPDLGGRFN RSLWQAYVSV 180 NKIFADRIME VINPEDDFVW VHDYHLMVLP TFLRKRFNRA KLGFFLHSPF PSSEIYKTLP 240 VREEILRALL NSDLIGFHTF DYARHFLSCC SRMLGLTYES KRGYIGLEYY GRTVSIKILP 300 VGIHMGQLQS VLSLPETEAK VAELIKQFSD QGRTMLLGVD DMDIFKGISL KLLAMEQLLV 360 QHPEWQGKVV LVQIANPARG RGKDVKEVQA ETSSTVKRIN ETFGRPGYKP VVLIDEPLKF 420 YERIAYYVVA ECCLVTAVRD GMNLIPYEYI IGRQGNSKLD KVLGLEPSIP KKSMLVVSEF 480 IGCSPSLSGA IRVNPWNIDA VADAMDCALE MAEPEKQLRH EKHYRYVSTH DVGYWARSFL 540 QDLERTCKGH LRQRSWGIGF GLSFRVVALG PNFRKLSMEH IVSAYRRTAT RAILLDYDGT 600 LMPQASIDKS PTSKSIEILN SLCRDKNNMV FIVSAKSRKV LAEWFSPCEK LGIAAEHGYF 660 LRLKRDAEWE TCVPVADSSW KQIAEPVMKL YTETTDGSTI EDKETALVWC YEDADPDFGS 720 CQAKELLDHL ESVLANEPVT VKTGQNVVEV KPQGVNKGLV AKRLLSTMQE REMSPDFVLC 780 IGDDRSDEDM FEVITSSISG PSIAPRAEVF ACTVCKKPSK AKYYLDDVAE IVRLMQGLAC 840 VSEQTVPL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 4.0e-174 | 7 | 804 | 831 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 848 | 854 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 55 | 545 | 493 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
cd03788 | GT1_TPS | 0 | 55 | 544 | 490 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
PRK14501 | PRK14501 | 0 | 55 | 839 | 793 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG52003.1 | 0 | 1 | 848 | 1 | 847 | AC012563_13 putative trehalose-6-phosphate synthase; 46897-44149 [Arabidopsis thaliana] |
RefSeq | NP_974105.1 | 0 | 1 | 848 | 1 | 860 | ATTPS6; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
RefSeq | XP_002284972.1 | 0 | 1 | 848 | 1 | 854 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002312472.1 | 0 | 1 | 846 | 1 | 849 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002314777.1 | 0 | 1 | 846 | 1 | 838 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 142 | 545 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 142 | 545 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 142 | 545 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 142 | 545 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 142 | 545 | 76 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 771 | 77 | 846 | 0 |
HO779327 | 517 | 98 | 614 | 0 |
HO779327 | 236 | 608 | 843 | 0 |
HO795560 | 431 | 419 | 848 | 0 |
HO777775 | 78 | 1 | 72 | 0.0000000000005 |
Sequence Alignments (This image is cropped. Click for full image.) |
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