Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000919905 |
Family | GT20 |
Protein Properties | Length: 768 Molecular Weight: 87390.2 Isoelectric Point: 6.0898 |
Chromosome | Chromosome/Scaffold: 018744266 Start: 67 End: 2799 |
Description | trehalose-phosphatase/synthase 7 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 9 | 456 | 0 |
GLPEDMEVLYVGSLKVSVDPKEQDDVSQVLLERFKCVPTFLPPDILSKFYDGFCKRHLWPLFHYMLPFSADQGGRFDRSLWEAYISANKLFFQRVVELIN PDEDYIWIHDYHLMVLPTFLRRRFNRVRMGFFLHSPFPSSEIYRTLPVREEILKALLNADIIGFHTFDYARHFLTCCSRMLGLVYQSKRGYLGLEYYGRN IRIKIMPVGVHMGWIESVMKVADDESRVRELTQQFEGKTMLLGIDDMDIFKGINLKILAMEQMLKQHPNWQGKAVLVQILNPVRGKGIDLEEIRAEIQES CRRINAEFGQPGYEPIIIIDRPVSINEKICYYNIAECVVVTAVRDGMNLTPYEYVVCRQGISGSNSCSNFGGPKKSMLVVSEFIGCSPSLSGAIRVNPWN VETTGEALNVAISVLDSEKELRHEKHYRYVSTHDVAYWSRSFLQDMQR |
Full Sequence |
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Protein Sequence Length: 768 Download |
MIKLVLKDGL PEDMEVLYVG SLKVSVDPKE QDDVSQVLLE RFKCVPTFLP PDILSKFYDG 60 FCKRHLWPLF HYMLPFSADQ GGRFDRSLWE AYISANKLFF QRVVELINPD EDYIWIHDYH 120 LMVLPTFLRR RFNRVRMGFF LHSPFPSSEI YRTLPVREEI LKALLNADII GFHTFDYARH 180 FLTCCSRMLG LVYQSKRGYL GLEYYGRNIR IKIMPVGVHM GWIESVMKVA DDESRVRELT 240 QQFEGKTMLL GIDDMDIFKG INLKILAMEQ MLKQHPNWQG KAVLVQILNP VRGKGIDLEE 300 IRAEIQESCR RINAEFGQPG YEPIIIIDRP VSINEKICYY NIAECVVVTA VRDGMNLTPY 360 EYVVCRQGIS GSNSCSNFGG PKKSMLVVSE FIGCSPSLSG AIRVNPWNVE TTGEALNVAI 420 SVLDSEKELR HEKHYRYVST HDVAYWSRSF LQDMQRACAD HFKRRCWGIG FGFGFRVVAL 480 DPNFRKLSID AIVSAYRGAQ NRAILLDYDG TVMPQNSIDK SPSQKVISIM NTLCVDPKNT 540 VFIVTGRGRE CLSKWFSPCQ RMGIAAEHGY FLRWSQNQEW ETCLQGFEFG WMKTVEPVMQ 600 LYTEATDGSS IERKESALVW QYRDADPGFG SSQAKEMLDH LESVLANEPV AVKNGQFIVE 660 VKPQGVSKGH VAEKIFSSMA ENGKHADFVL CIGDDRSDED MFEIFGNSMQ KKVLSPNPSV 720 FACTVGQKPS KATYYLDDTA EVTNMLESLS EAFESLPPTE EGYESSP* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 4.0e-164 | 15 | 752 | 778 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 4 | 758 | 760 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 4 | 456 | 456 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 8 | 752 | 754 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 8 | 455 | 448 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN67058.1 | 0 | 4 | 761 | 92 | 849 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_172129.1 | 0 | 4 | 755 | 90 | 839 | ATTPS7; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
RefSeq | XP_002268174.1 | 0 | 4 | 767 | 91 | 853 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002305726.1 | 0 | 4 | 757 | 90 | 843 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522255.1 | 0 | 4 | 752 | 94 | 842 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 54 | 456 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 54 | 456 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 54 | 456 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 54 | 456 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1gz5_D | 0 | 54 | 456 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 759 | 4 | 756 | 0 |
HO779327 | 515 | 13 | 525 | 0 |
HO779327 | 239 | 519 | 757 | 0 |
HO795511 | 481 | 286 | 766 | 0 |
HO797286 | 472 | 289 | 754 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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