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Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr1g061760.1 |
Family | GT47 |
Protein Properties | Length: 509 Molecular Weight: 58458.3 Isoelectric Point: 9.0751 |
Chromosome | Chromosome/Scaffold: 1 Start: 15793503 End: 15796373 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 175 | 457 | 0 |
EKQFKVFVYEEGEPPVFHNGPCKSIYSMEGNFIHAIELNDQFRTRDPQKAHVYFLPFSVVMLVRFVYLRDSRDFGPIRKTVTDYINVIAGKYPYWNRSLG ADHFMLACHDWGPETSFSVPYLHKNSIRVLCNANTSERFNPAKDVSFPEINLQTGSINGFLGGLSASKRPILAFFAGGLHGHIRAILLEHWENNKDQDMM IQKYLPKGVSYYEMLRKSKFCLCPSGYEVASPRIVEAIYTGCVPVLISDHYVPPFSDVLNWKSFSVEISVEDIPKLKDILMRI |
Full Sequence |
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Protein Sequence Length: 509 Download |
MCNGERNCCV LRSGSKTSSS MKLFLSMVPL ILVAVVGIVS ILSPKERGEI VDLRSQAVQF 60 EMNSSHIAFN HSSSTPFPVH PIHTLQQSNE TEVLNISKPW LNSTVPLNET YVAHPRLKQQ 120 RKFSILDRTE AGLLHARAAI REASYSTQTQ DPDYVPIGPM YWNAKAFHRS YLEMEKQFKV 180 FVYEEGEPPV FHNGPCKSIY SMEGNFIHAI ELNDQFRTRD PQKAHVYFLP FSVVMLVRFV 240 YLRDSRDFGP IRKTVTDYIN VIAGKYPYWN RSLGADHFML ACHDWGPETS FSVPYLHKNS 300 IRVLCNANTS ERFNPAKDVS FPEINLQTGS INGFLGGLSA SKRPILAFFA GGLHGHIRAI 360 LLEHWENNKD QDMMIQKYLP KGVSYYEMLR KSKFCLCPSG YEVASPRIVE AIYTGCVPVL 420 ISDHYVPPFS DVLNWKSFSV EISVEDIPKL KDILMRISPT QYIRMQRRVV QIRRHFEVHS 480 PPKRFDVFHM ILHSVWLRRL NFRVHDDQ* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-66 | 174 | 457 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 118 | 506 | 20 | 407 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 118 | 506 | 130 | 517 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 174 | 505 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 174 | 501 | 1 | 327 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 147 | 508 | 209 | 569 | catalytic, putative [Ricinus communis] |