| Basic Information | |
|---|---|
| Species | Medicago truncatula |
| Cazyme ID | Medtr1g098640.3 |
| Family | GT1 |
| Protein Properties | Length: 587 Molecular Weight: 65078.7 Isoelectric Point: 6.038 |
| Chromosome | Chromosome/Scaffold: 1 Start: 28356059 End: 28363543 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT1 | 202 | 574 | 0 |
| VLAYVMFAMEYGHRVRLAAHANFKTFVRSAGVNFYPLGGDPRVLAGYMARNKGLIPSGPTEISIQRKQLKVIIDSLLPACTAPDLETGIPFTAQAIIANP PAYGHVHLAEALGVPIHIFFTMPWTPTYAFPHPLARVSQGAGYWLSYIIVDLLIWWGMRGIINDFRKRTLKLAPIAYFSMYRGSISHLPTAYMWSPHLVP KPSDWGSLVDVVGYCFLRHESNYQPREDFLHWIKKGPPPLYFGFGSMPLEDPKITTDVILKALKETEQRGIIDRGWGNLGNLTEVSDNVFLLEECPHDWL FPQCSAVVHHGGAGTTATGLKSGCPTTIVPFFGDQFFWGDRIHQKELGPAPIPISELNVENLSNAIKFMLQPE | |||
| Full Sequence |
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| Protein Sequence Length: 587 Download |
| MGCNGIEHLC TEVVEDEKGL RKMDDDKLVS VRGEIMSQED DGSPSSKERG SQSSEVTSLP 60 HRGLEHCITA PIGTERNPLI AEDEIMISRS MTEKRGLRRH DLLLDRLSED EKQKLIANLV 120 KIQKDGTVQV DIETSASVAS ELLEFQSFEE SVASGNFIIS DSNKSVPRLQ IVILVVGTRG 180 DVQPFVAIAK RLQEMFYAVC DVLAYVMFAM EYGHRVRLAA HANFKTFVRS AGVNFYPLGG 240 DPRVLAGYMA RNKGLIPSGP TEISIQRKQL KVIIDSLLPA CTAPDLETGI PFTAQAIIAN 300 PPAYGHVHLA EALGVPIHIF FTMPWTPTYA FPHPLARVSQ GAGYWLSYII VDLLIWWGMR 360 GIINDFRKRT LKLAPIAYFS MYRGSISHLP TAYMWSPHLV PKPSDWGSLV DVVGYCFLRH 420 ESNYQPREDF LHWIKKGPPP LYFGFGSMPL EDPKITTDVI LKALKETEQR GIIDRGWGNL 480 GNLTEVSDNV FLLEECPHDW LFPQCSAVVH HGGAGTTATG LKSGCPTTIV PFFGDQFFWG 540 DRIHQKELGP APIPISELNV ENLSNAIKFM LQPECISGEI SDNGSC* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 3.0e-26 | 171 | 576 | 419 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 2.0e-31 | 171 | 332 | 162 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 8.0e-110 | 171 | 574 | 404 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABC96116.1 | 0 | 46 | 577 | 124 | 638 | sterol glucosyltransferase [Withania somnifera] |
| EMBL | CBI18214.1 | 0 | 1 | 577 | 68 | 635 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265312.1 | 0 | 1 | 577 | 52 | 619 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002302172.1 | 0 | 1 | 577 | 1 | 554 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524293.1 | 0 | 64 | 577 | 18 | 515 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 1e-22 | 169 | 585 | 1 | 370 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 3h4i_A | 1e-22 | 169 | 585 | 1 | 370 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 1e-20 | 169 | 586 | 1 | 388 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1rrv_B | 5e-17 | 169 | 574 | 1 | 371 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 5e-17 | 169 | 574 | 1 | 371 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DT547914 | 339 | 187 | 525 | 0 |
| HO801427 | 374 | 215 | 581 | 0 |
| CO103793 | 293 | 182 | 474 | 0 |
| GT172550 | 313 | 158 | 470 | 0 |
| HO801427 | 26 | 169 | 194 | 0.006 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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