| Basic Information | |
|---|---|
| Species | Medicago truncatula |
| Cazyme ID | Medtr2g099470.1 |
| Family | GH19 |
| Protein Properties | Length: 554 Molecular Weight: 60162.4 Isoelectric Point: 4.6634 |
| Chromosome | Chromosome/Scaffold: 2 Start: 31489436 End: 31496031 |
| Description | homolog of carrot EP3-3 chitinase |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 80 | 281 | 0 |
| NVADILTQDFFNRIIDQADSSCAGKNFYTRAAFLDALNSYNQFGRSGSLDDSKREVAAAFAHFTHETGHFCYTEEIDGPSKDYCDEGNTEWPCAPNKGYY GRGPIQLSWNYNYGPAGRDNGFDGLNSPETVANDPTVSFKTALWYWMNNVHGVINQGFGATIRAINGRLECDGANPSTVQTRVGYYTQYCSELGVAPGDN LT | |||
| GH19 | 351 | 553 | 0 |
| VADIVTQEFFNSIIDQADSSCAGKNFYSRAVFLDALGSYNQFGRVGSVDDSKREIAAAFAHFTHETGHFCYIEEKDGASKDYCDESNTEYPCAPNKGYYG RGPIQLSWNFNYGPAGKDSGFDELNSPETVANDPLVSFKTALWYWMNHVHNVMNQQGFGATVRAINGRLECDGVDPNTVKARVDYYTQYCSQLGVAPGDK LNC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 554 Download |
| MTMMGNKSLS ICMATLAIAF FIMIMVPKNV SAQNCGCAEG VCCSQYGYCG NGDAYCGTGC 60 KQGPCYAGQT PPSLPNNDAN VADILTQDFF NRIIDQADSS CAGKNFYTRA AFLDALNSYN 120 QFGRSGSLDD SKREVAAAFA HFTHETGHFC YTEEIDGPSK DYCDEGNTEW PCAPNKGYYG 180 RGPIQLSWNY NYGPAGRDNG FDGLNSPETV ANDPTVSFKT ALWYWMNNVH GVINQGFGAT 240 IRAINGRLEC DGANPSTVQT RVGYYTQYCS ELGVAPGDNL TFTKHVYSKT CYNLSKNTSA 300 QNCGCEEGLC CSEHGYCGNT DPYCGTGCKQ GPCYAGQISP STPGPSNDVN VADIVTQEFF 360 NSIIDQADSS CAGKNFYSRA VFLDALGSYN QFGRVGSVDD SKREIAAAFA HFTHETGHFC 420 YIEEKDGASK DYCDESNTEY PCAPNKGYYG RGPIQLSWNF NYGPAGKDSG FDELNSPETV 480 ANDPLVSFKT ALWYWMNHVH NVMNQQGFGA TVRAINGRLE CDGVDPNTVK ARVDYYTQYC 540 SQLGVAPGDK LNC* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00442 | lysozyme_like | 9.0e-9 | 171 | 227 | 57 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-87 | 354 | 553 | 232 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 8.0e-91 | 355 | 553 | 230 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 3.0e-93 | 84 | 281 | 231 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 2.0e-99 | 86 | 281 | 228 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAR87869.1 | 0 | 1 | 281 | 1 | 281 | class IV chitinase precursor [Medicago truncatula] |
| GenBank | AAR87869.1 | 0 | 294 | 553 | 26 | 282 | class IV chitinase precursor [Medicago truncatula] |
| GenBank | ACL36992.1 | 0 | 1 | 281 | 1 | 281 | class IV chitinase [Medicago sativa] |
| GenBank | ACL36992.1 | 0 | 294 | 553 | 26 | 282 | class IV chitinase [Medicago sativa] |
| GenBank | ACU23323.1 | 0 | 3 | 281 | 1 | 273 | unknown [Glycine max] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 81 | 281 | 2 | 203 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 3hbh_A | 0 | 351 | 553 | 2 | 204 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 3hbe_X | 0 | 81 | 281 | 2 | 203 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 3hbe_X | 0 | 351 | 553 | 2 | 204 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 3hbd_A | 0 | 81 | 281 | 2 | 203 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
