Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr2g100070.1 |
Family | AA3 |
Protein Properties | Length: 595 Molecular Weight: 65217.9 Isoelectric Point: 9.8087 |
Chromosome | Chromosome/Scaffold: 2 Start: 31815334 End: 31820971 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 54 | 587 | 0 |
ISTTNTNDGYDYIIVGGGTAGCPLAATLSQNFNVLLLERGGVPFTNPNVSFLDNFHITLADISPTSASQFFLSTDGVFNARARVLGGGSSINAGFYTRAS SRFIQKMGWDTKLVNKSYPWVEKQIVHRPTFSHWQRAFRDGLLDAGVSPFNGFTYEHKYGTKVGGTIFDRFGRRHTAAELLSSGNPNKLTVLIYATVQKI VFDTTGKRPKAMGVIFKDENGKQHKAILGNDRESEVIVSSGAIGTPQMLLLSGIGPKAELENLKIPVVLDNRFVGKGMADNPMNTIFVPLKKSVKQSLIE TVGITNKGVYIEASCGFGQTNDSIHCHHGLLSAEIGQLSTIPPKQRSAESIKAFVKNKKDIPIEAFKGGFILSKVANPWSTGDLKLINTNVDDNPAVTFN YFSHPYDLHRCVEGIRLATKVVQSQHFTNLTLCEKQTTEQLLNNTVKANINLIPKHVNDTESLEQFCRDTVITIWHYHGGCHVGKVIDSDHKVLGVNRLR VIDGSTFTESPGTNPQATVMMMGRYMGVKILRDR |
Full Sequence |
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Protein Sequence Length: 595 Download |
MATLGAVKFL LCLLMIWLIN FLPLCQGLGK QNLNNGYKYP FIRKASSFSS PPSISTTNTN 60 DGYDYIIVGG GTAGCPLAAT LSQNFNVLLL ERGGVPFTNP NVSFLDNFHI TLADISPTSA 120 SQFFLSTDGV FNARARVLGG GSSINAGFYT RASSRFIQKM GWDTKLVNKS YPWVEKQIVH 180 RPTFSHWQRA FRDGLLDAGV SPFNGFTYEH KYGTKVGGTI FDRFGRRHTA AELLSSGNPN 240 KLTVLIYATV QKIVFDTTGK RPKAMGVIFK DENGKQHKAI LGNDRESEVI VSSGAIGTPQ 300 MLLLSGIGPK AELENLKIPV VLDNRFVGKG MADNPMNTIF VPLKKSVKQS LIETVGITNK 360 GVYIEASCGF GQTNDSIHCH HGLLSAEIGQ LSTIPPKQRS AESIKAFVKN KKDIPIEAFK 420 GGFILSKVAN PWSTGDLKLI NTNVDDNPAV TFNYFSHPYD LHRCVEGIRL ATKVVQSQHF 480 TNLTLCEKQT TEQLLNNTVK ANINLIPKHV NDTESLEQFC RDTVITIWHY HGGCHVGKVI 540 DSDHKVLGVN RLRVIDGSTF TESPGTNPQA TVMMMGRYMG VKILRDRLGK LAGV* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 3.0e-27 | 63 | 333 | 321 | + choline dehydrogenase; Validated | ||
TIGR03970 | Rv0697 | 2.0e-32 | 64 | 576 | 562 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 2.0e-34 | 64 | 576 | 586 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 1.0e-48 | 63 | 587 | 591 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 21 | 594 | 577 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABN08391.1 | 0 | 159 | 594 | 6 | 441 | ABC transporter related; Choline dehydrogenase [Medicago truncatula] |
EMBL | CBI35951.1 | 0 | 25 | 594 | 24 | 593 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002327436.1 | 0 | 58 | 594 | 12 | 547 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329018.1 | 0 | 37 | 594 | 32 | 591 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 39 | 593 | 41 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 63 | 587 | 27 | 517 | A Chain A, Crystal Structure Of A Native Endo Beta-1,3-Glucanase (Hev B 2), A Major Allergen From Hevea Brasiliensis |
PDB | 3gdp_A | 0 | 63 | 587 | 27 | 517 | A Chain A, Crystal Structure Of A Native Endo Beta-1,3-Glucanase (Hev B 2), A Major Allergen From Hevea Brasiliensis |
PDB | 3gdn_B | 0 | 63 | 587 | 27 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 63 | 587 | 27 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 63 | 587 | 27 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |