Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr3g085480.1 |
Family | GT47 |
Protein Properties | Length: 426 Molecular Weight: 49182.1 Isoelectric Point: 7.5159 |
Chromosome | Chromosome/Scaffold: 3 Start: 27901416 End: 27903628 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 47 | 359 | 0 |
EAPLRVYMYDLPRRFNVGMLDGRNTTEAPVTIADYPLWPDNQGLRRQHSVEYWMMGSLLNGGGNGSEAVRVLDPEVVDVYFVPFFSSLSFNTHGHHMRDP ETEIDHQLQIDLMGLLGQSKYWQRSGGRDHIFPMTHPNAFRFLRDQLNESIQVVVDFGRYPKGVSNLNKDVVSPYVHFVDSYVDDEPHDPFESRTTLLFF RGGTHRKDKGIVRAKFTKILAGFDDVHYERSSATGENIKLSSKGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDKIELPFENEIDYSQFSLFFSF KEALEPGYMINQL |
Full Sequence |
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Protein Sequence Length: 426 Download |
MLGKVVIFFT LALLIFIPCS ILIGTLDIRS YYQQSPSIIA TTPCADEAPL RVYMYDLPRR 60 FNVGMLDGRN TTEAPVTIAD YPLWPDNQGL RRQHSVEYWM MGSLLNGGGN GSEAVRVLDP 120 EVVDVYFVPF FSSLSFNTHG HHMRDPETEI DHQLQIDLMG LLGQSKYWQR SGGRDHIFPM 180 THPNAFRFLR DQLNESIQVV VDFGRYPKGV SNLNKDVVSP YVHFVDSYVD DEPHDPFESR 240 TTLLFFRGGT HRKDKGIVRA KFTKILAGFD DVHYERSSAT GENIKLSSKG MRSSKFCLHP 300 AGDTPSSCRL FDAIVSHCVP VIVSDKIELP FENEIDYSQF SLFFSFKEAL EPGYMINQLR 360 SFPKQNWTEM WRQLKNISHH YEFHYPPERE DAVNMLWRQI KHKLPGIRQS VHRSQRLKIP 420 DWWKR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-61 | 48 | 362 | 323 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 1 | 404 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 1 | 423 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 27 | 423 | 27 | 426 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 49 | 423 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 25 | 425 | 25 | 433 | catalytic, putative [Ricinus communis] |