Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr4g035360.1 |
Family | CE16 |
Protein Properties | Length: 1005 Molecular Weight: 113001 Isoelectric Point: 8.0953 |
Chromosome | Chromosome/Scaffold: 4 Start: 11089832 End: 11101709 |
Description | GDSL-like Lipase/Acylhydrolase superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CE16 | 676 | 982 | 1.6e-21 |
FGDSLVEVGNNNFLSTFAKSNFYPYGIDYNGRPTGRFSNGKSLIDFIGDMLGVPSPPPFLDPTSTENKLLNGVNYASGSGGILDDSGRHYGDRHSMSRQL QNFERTLNQYKKMMNETALSQFLAKSIVIVVTGSNDYINNYLRPEYYGTSRNYSVPQFGNLLLNTFGRQILALYSLGLRKFFLAGVGPLGCIPNQRANGF APPGRCVDSVNQMVGTYNGGLRSMVEQFNRDHSDAKFVYGNTYGVFGDILNNPAAYAFSVIDRACCGLGRNRGQISCLPMQFPCANRAQYVFWDAFHPTQ SATYVFA |
Full Sequence |
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Protein Sequence Length: 1005 Download |
MDNSKWLLGN GRLIKFWEDA WCGEPLHETL NVNQDIYREY PQFVHDYIQN FRWHIPQTIL 60 VHYPALKLLA EKVTIPMEDK EDKLIWNHNS NGDLMMRDSY AFKNQPVNTH NWAKLIWSKD 120 IPPSKSILTW RLIHDKVPTD EKLQQRGCQL PSMCSLCGTH VETSFHLFFE CCFAFRIWCW 180 FASVLDSSLH FQSIPDIWSV CDRGWSPQCK VVNQATIVNI ISTIWYNRNQ RWIKFNTDGA 240 STATSSSCGG VFRDQNANFL SCFAKNLGGG SAYQPELAAI MRVVEIAYQR NWRNIWIESD 300 SALVVMAFKK MSMIPCRLRN RWINCRKLLC RMNFVITHIY REDNRCADKL ASKGLDIEGV 360 TIWLNMPDFI NNFVIHDRLG MCDHTSTNAP DPIRTPQLSV LGCDHTSTNA PDPIRTPQLS 420 VLGCDHTSTN APDPIKTPQL SVLGCDHTST NAPDPIRTPQ LSVLGSKSVA DFNRTRAQKV 480 PNRWPIFHDA KAQNCSKNRW CVHTSTDAPD PIRTPQLSVL GCVHTSTDAP DPIRTPQLRV 540 LGCVHTSTDA PDPIRTLQLS VLGFVYTSTD APDPIRTPQL SVLGFHQNSV VKRAWARVVL 600 GWVTFWEVLV LCDHTSTDAP DSSESSTRMG DLLGSPCITI QMKGVSEYMV LLVLVLQCFN 660 MVVKVNSQKV PGMFVFGDSL VEVGNNNFLS TFAKSNFYPY GIDYNGRPTG RFSNGKSLID 720 FIGDMLGVPS PPPFLDPTST ENKLLNGVNY ASGSGGILDD SGRHYGDRHS MSRQLQNFER 780 TLNQYKKMMN ETALSQFLAK SIVIVVTGSN DYINNYLRPE YYGTSRNYSV PQFGNLLLNT 840 FGRQILALYS LGLRKFFLAG VGPLGCIPNQ RANGFAPPGR CVDSVNQMVG TYNGGLRSMV 900 EQFNRDHSDA KFVYGNTYGV FGDILNNPAA YAFSVIDRAC CGLGRNRGQI SCLPMQFPCA 960 NRAQYVFWDA FHPTQSATYV FAWRAVNGPQ NDAYPINIQQ LAQM* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
cd06222 | RNase_H | 3.0e-19 | 236 | 355 | 123 | + RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. Ribonuclease H (RNase H) enzymes are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, Type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication, repair and transcription. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription. |
pfam13966 | zf-RVT | 2.0e-19 | 97 | 178 | 82 | + zinc-binding in reverse transcriptase. This domain would appear to be a zinc-binding region of a putative reverse transcriptase. |
cd01846 | fatty_acyltransferase_like | 2.0e-33 | 673 | 987 | 316 | + Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols. |
PLN03156 | PLN03156 | 7.0e-71 | 648 | 975 | 333 | + GDSL esterase/lipase; Provisional |
cd01837 | SGNH_plant_lipase_like | 2.0e-122 | 671 | 989 | 320 | + SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. |
Gene Ontology | |
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GO Term | Description |
GO:0003676 | nucleic acid binding |
GO:0004523 | ribonuclease H activity |
GO:0006629 | lipid metabolic process |
GO:0016788 | hydrolase activity, acting on ester bonds |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN77693.1 | 0 | 667 | 1002 | 29 | 383 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_177281.1 | 0 | 645 | 1004 | 12 | 373 | GDSL-motif lipase/hydrolase family protein [Arabidopsis thaliana] |
RefSeq | XP_002266194.1 | 0 | 667 | 1002 | 29 | 361 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002329215.1 | 0 | 649 | 1001 | 1 | 350 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002521611.1 | 0 | 665 | 1001 | 28 | 364 | zinc finger protein, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
BI310141 | 263 | 697 | 959 | 0 |
DV158828 | 291 | 639 | 927 | 0 |
GT626747 | 207 | 799 | 1005 | 0 |
DW115416 | 289 | 637 | 924 | 0 |
DV159058 | 288 | 639 | 924 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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