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Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr4g078020.1 |
Family | GT47 |
Protein Properties | Length: 1199 Molecular Weight: 132538 Isoelectric Point: 8.5219 |
Chromosome | Chromosome/Scaffold: 4 Start: 25535573 End: 25543550 |
Description | cation/H+ exchanger 19 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 112 | 422 | 0 |
LKVYVYNMPNKFTYDLLLLFRNTYRDTSNLTSNGSPVHRLIEQHSIDYWLWADLIAPESERLLKSVVRVHRQEEADFFYIPFFTTISFFLLEKQQCKALY REALKWITDQPAWKRSGGRDHILPVHHPWSFKTVRRYVKKAIWLLPDMDSTGNWYKPGQVYLEKDLILPYVANVDFCDATCLSEINPKRNTLLFFRGRLK RNAGGKIRSKLVDQLRGADGVVIEEGTSGEGGKEAAQNGMRKSLFCLNPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIALFVSSNDALK PSWLLKYLKDI |
Full Sequence |
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Protein Sequence Length: 1199 Download |
MAGKQISRSK SRIILLSLSL LGFSLLIFLS SLSPLRTTSP SSTHFHLPTT SHTSFVTSLE 60 HFLKTHPSPS LPDDTPHKPL TDQHVTNLDN SVFHSETNRL NSDPFYPISL PLKVYVYNMP 120 NKFTYDLLLL FRNTYRDTSN LTSNGSPVHR LIEQHSIDYW LWADLIAPES ERLLKSVVRV 180 HRQEEADFFY IPFFTTISFF LLEKQQCKAL YREALKWITD QPAWKRSGGR DHILPVHHPW 240 SFKTVRRYVK KAIWLLPDMD STGNWYKPGQ VYLEKDLILP YVANVDFCDA TCLSEINPKR 300 NTLLFFRGRL KRNAGGKIRS KLVDQLRGAD GVVIEEGTSG EGGKEAAQNG MRKSLFCLNP 360 AGDTPSSARL FDAIVSGCIP VIVSDELELP FEGILDYRKI ALFVSSNDAL KPSWLLKYLK 420 DIRSAHIKEM QQNLAKYSRH FLYSSPAQPL GPEDLVWKMM AGKVVNIKLT VLDTLANIGL 480 LFFLFLVGLE LDMRSIRKTG SKALCIALAG ITVPFVLGIG TSLVLRATIN KDANPTSFLV 540 FMGVALSITA FPVLARILAE LKLLTTDVGR MAMSAAAVND VAAWILLALA VALSGANTSP 600 LVSLWVLLCG VGFILFVIFA IKPLLAIMAK RCPEGEPVKE IYICITLTLV LGCSFLTDTI 660 GIHALFGAFV AGIVVPKEGP FASILTEKIE DLVMSLLLPL YFVSSGLKTN VATISGALSW 720 GLLILVIFTA CFGKVVGTLV VSLLCKIPFR EALTLGFLMN TKGLVELIVL NIGKDRKVLS 780 DQAFAICVVM ALVTTFITTP IVMAVYKPAR RGSPYMHKTI QRKDPDTELR ILACFHSTYN 840 IPTLINLIES SRGTRKRGKL CIYAMHLMEL SERPSAITMV HKARNNGLPF WNKKQHDNKD 900 QMVIAFQAYG HLSSVNVRSM TAISSLNNIH EDICSSAHQK RVAMILLPFH KHQRVDGTME 960 SLGHSFRVMN GLVLSHAPCS VGILVDRGLG GTTQVHASDV SYNVVVAFFG GCDDREALAY 1020 GMRIAEHPGI SLTVLKFITP PGKTLAFGAK LIGITADRDR KVIKVSDGNT PDEDKQEDDQ 1080 FWSEFLGVCC KSEESIVYEE RLVESKEDIV TVLSERNKSN LILAGRMPPV APLLDGSDCA 1140 ELGPVGSYLA SSEFSTFASV IIFQQYDPKT DIHPLVMEVS DYSNMPDTPV HGVSVHGV* 1200 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0475 | KefB | 4.0e-40 | 471 | 813 | 349 | + Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism] | ||
pfam00999 | Na_H_Exchanger | 1.0e-47 | 471 | 802 | 334 | + Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family. | ||
pfam03016 | Exostosin | 7.0e-68 | 111 | 422 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
PLN03159 | PLN03159 | 0 | 469 | 1166 | 705 | + cation/H(+) antiporter 15; Provisional |
Gene Ontology | |
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GO Term | Description |
GO:0006812 | cation transport |
GO:0015299 | solute:hydrogen antiporter activity |
GO:0016020 | membrane |
GO:0016021 | integral to membrane |
GO:0055085 | transmembrane transport |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_188390.2 | 0 | 469 | 1184 | 92 | 790 | ATCHX19 (CATION/H+ EXCHANGER 19); monovalent cation:proton antiporter/ sodium:hydrogen antiporter [Arabidopsis thaliana] |
RefSeq | XP_002270854.1 | 0 | 469 | 1187 | 92 | 798 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002314344.1 | 0 | 469 | 1171 | 79 | 758 | cation proton exchanger [Populus trichocarpa] |
RefSeq | XP_002314350.1 | 0 | 469 | 1167 | 79 | 752 | cation proton exchanger [Populus trichocarpa] |
RefSeq | XP_002509894.1 | 0 | 469 | 1172 | 94 | 787 | Na(+)/H(+) antiporter, putative [Ricinus communis] |