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Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr4g100730.1 |
Family | GT47 |
Protein Properties | Length: 536 Molecular Weight: 62115.2 Isoelectric Point: 10.0821 |
Chromosome | Chromosome/Scaffold: 4 Start: 34721768 End: 34725835 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 203 | 489 | 0 |
VLKVYIYRDGSRPIFHNPSLKGIYASEGWFMKLMQENKQFVTKDPERAHLFYLPYSARQMEVTLYVPGSHDLKPLSIFLRDYVNKIAAKYPFWNRTHGSD HFLVACHDWGPYTVTEHEELARNTLKALCNADLSERIFIEGRDVSLPETTIRAPRRPLRYLGGNRASLRPILAFFAGSMHGRVRPTLLKYWGGEKYEDMK IYKRLPLRVSKKMTYIQHMKSSKYCLCPMGFEVNSPRIVEAIYYECVPVIIADNFVLPLSEVLDWSAFSVVVAEKDIPRLKDILLSI |
Full Sequence |
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Protein Sequence Length: 536 Download |
MKKVFHLTVI ILMRELSWRC FRHKIDWRRL FLLVSIFTAS GFVFQMIVHT SVISPNKHFH 60 FPPGAADSYK SSNSTIQSNE FIKETILQNV HLTLPNSAVS PKLSNNFVQS VSVEADSINT 120 EARRKKDRNL ANTSTTVTTS FPRGRVPSGK QTDIRLITPT EALVYARKEI DHVTSVNEDP 180 DLYAPLFRNV SVFKRSYELM ETVLKVYIYR DGSRPIFHNP SLKGIYASEG WFMKLMQENK 240 QFVTKDPERA HLFYLPYSAR QMEVTLYVPG SHDLKPLSIF LRDYVNKIAA KYPFWNRTHG 300 SDHFLVACHD WGPYTVTEHE ELARNTLKAL CNADLSERIF IEGRDVSLPE TTIRAPRRPL 360 RYLGGNRASL RPILAFFAGS MHGRVRPTLL KYWGGEKYED MKIYKRLPLR VSKKMTYIQH 420 MKSSKYCLCP MGFEVNSPRI VEAIYYECVP VIIADNFVLP LSEVLDWSAF SVVVAEKDIP 480 RLKDILLSIP MRKYVAMQNN VKMVQKHFLW NPKPIRYDLF HMILHSIWLN KLNQI* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-65 | 204 | 489 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 1 | 535 | 1 | 533 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 142 | 534 | 139 | 530 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 1 | 535 | 1 | 533 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 157 | 535 | 3 | 381 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 12 | 535 | 1 | 523 | catalytic, putative [Ricinus communis] |