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Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr4g115530.1 |
Family | GT47 |
Protein Properties | Length: 399 Molecular Weight: 46322.5 Isoelectric Point: 10.0489 |
Chromosome | Chromosome/Scaffold: 4 Start: 39934184 End: 39935557 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 57 | 343 | 0 |
KRFKVWVYKEGEQPLVHDGPVNNKYSIEGQFIDEMDTSNKSPFKATHPELAHVFFLPFSVSKVIRYVYKPRKSRSDYNPHRLQLLVEDYIKIVANKYPYW NISQGADHFLLSCHDWGPRVSYANPKLFKHFIRALCNANTSEGFWPNRDVSIPQLNLPVGKLGPPNTDQHPNNRTILTFFAGGAHGKIRKKLLKSWKDKD EEVQVHEYLPKGQDYTKLMGLSKFCLCPSGHEVASPRVVEAIYAGCVPVIICDNYSLPFSDVLNWSQFSMEIAVDRIPEIKTILQNI |
Full Sequence |
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Protein Sequence Length: 399 Download |
MTSLEKIEED LAQTRALIQR AIRSKKSTTN MKQSFVPKGS IYLNPHAFHQ SHKEMVKRFK 60 VWVYKEGEQP LVHDGPVNNK YSIEGQFIDE MDTSNKSPFK ATHPELAHVF FLPFSVSKVI 120 RYVYKPRKSR SDYNPHRLQL LVEDYIKIVA NKYPYWNISQ GADHFLLSCH DWGPRVSYAN 180 PKLFKHFIRA LCNANTSEGF WPNRDVSIPQ LNLPVGKLGP PNTDQHPNNR TILTFFAGGA 240 HGKIRKKLLK SWKDKDEEVQ VHEYLPKGQD YTKLMGLSKF CLCPSGHEVA SPRVVEAIYA 300 GCVPVIICDN YSLPFSDVLN WSQFSMEIAV DRIPEIKTIL QNITETKYRV LYSNVRRVRK 360 HFEMNRPAKP FDLIHMILHS VWLRRLNFRL HLKQMYPS* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-65 | 55 | 343 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 1 | 398 | 76 | 473 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 1 | 390 | 234 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 4 | 392 | 15 | 402 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 2 | 390 | 86 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 2 | 390 | 5 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CA918365 | 194 | 1 | 194 | 0 |
EC939466 | 291 | 2 | 291 | 0 |
EY475927 | 106 | 67 | 172 | 0 |
CA918365 | 38 | 200 | 237 | 0.000000000005 |
CA918365 | 9 | 194 | 202 | 0.000000000005 |
Sequence Alignments (This image is cropped. Click for full image.) |
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