Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr4g115540.1 |
Family | GT47 |
Protein Properties | Length: 618 Molecular Weight: 71247.5 Isoelectric Point: 9.6248 |
Chromosome | Chromosome/Scaffold: 4 Start: 39936368 End: 39939965 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 280 | 566 | 0 |
KRLKIWVYQEGEQPIVHDGPVNNIYAIEGQFIDEIDNSKMSPFKAKHPNEAHIFFLPFSVANVVQYVYKPIMSKKDFNRDRLHRMVEDYVNVVAHKYPYW NRSNGADHFLLSCHDWAPEISDANPNLFKNFTRVLCNANTSEGFQPKRDVSIPEVYLPVGKLGPPNLGQSPLNRTILAFFSGGAHGDIRKLLLNHWKNKD AQVQVHEYLPKGQNYTELMGLSKFCLCPSGYEVASPRIVEAINAGCVPVIISQNYSLPFNDVLNWSEFSVEIPVEKIVEIKNILQNV |
Full Sequence |
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Protein Sequence Length: 618 Download |
MKKSLIICRM GYISMNGSGS SSFWSCPWCS LRFIESLAPC IDIHDMLLSV KDVFSSGSPH 60 AHILYTQLPS FAIDLINNMQ LNFNASAENA FIWTHNKNCI YTANSGYSWI LARMNSVINS 120 PLSWSWFWKL QSSKKIKFLF WQIFIQPATL KLSYMEALRC FTTSLLLPLF FFLIFLFTSQ 180 KGFHFSFFVF PFSLPSIKDM NNATQVIKPH QFLTYNSAYR SFDHKENSSI KKIMSSLDRV 240 EGSLSEARAS IREAILSRNY STSRRRDVFV PRGSHMEMVK RLKIWVYQEG EQPIVHDGPV 300 NNIYAIEGQF IDEIDNSKMS PFKAKHPNEA HIFFLPFSVA NVVQYVYKPI MSKKDFNRDR 360 LHRMVEDYVN VVAHKYPYWN RSNGADHFLL SCHDWAPEIS DANPNLFKNF TRVLCNANTS 420 EGFQPKRDVS IPEVYLPVGK LGPPNLGQSP LNRTILAFFS GGAHGDIRKL LLNHWKNKDA 480 QVQVHEYLPK GQNYTELMGL SKFCLCPSGY EVASPRIVEA INAGCVPVII SQNYSLPFND 540 VLNWSEFSVE IPVEKIVEIK NILQNVTKDK YMKLHMNVMK VQKHFVMNRP AKPFDVMHMI 600 LHSIWLRRLN FRLIDSK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-64 | 278 | 566 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA18105.1 | 0 | 232 | 613 | 27 | 421 | exostosin family protein [Capsella rubella] |
GenBank | ABP03872.1 | 0 | 201 | 613 | 50 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 1 | 617 | 1 | 617 | Exostosin-like [Medicago truncatula] |
EMBL | CBI25537.1 | 0 | 184 | 613 | 32 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 232 | 613 | 2 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |