Basic Information | |
---|---|
Species | Medicago truncatula |
Cazyme ID | Medtr4g119810.1 |
Family | GT47 |
Protein Properties | Length: 456 Molecular Weight: 52577.9 Isoelectric Point: 7.6373 |
Chromosome | Chromosome/Scaffold: 4 Start: 41482437 End: 41484056 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 42 | 396 | 0 |
CEQRWIHIRKLPPKFNLDLLSNCSEYTFLDDLCPYLANHGLGQKTHNRSHSWYRTDPSMLELIFHRRMLEYPCLTEDPKTANAVYLPYYAAFDSLRYLYG PEYNSSEQHGVHLFHFLTKENHPEIWNRHSGHDHFLVMARPAWDFAQPLDNDPHLWGTSFLELPHFFNVTALTLESRAWPWQEHAVPYPTSFHPPNLALL DSWIQRVRRSKRSSLALFAGGGGFSATPNIRRSIRMECDNDNNSSNVNGNSFGYEKLCETVDCSNGVCEHDPIRFMKPMLGANFCLQPPGDTPTRKSTFD AILAGCIPVFFEDLSAKSQYSWHLPENEFEGFSVTIPKEDVVFKGLKIFDVLQRI |
Full Sequence |
---|
Protein Sequence Length: 456 Download |
MAPSKPHISI YISIITIFLL LLNPTKSEEN KNLKSTTTEN ECEQRWIHIR KLPPKFNLDL 60 LSNCSEYTFL DDLCPYLANH GLGQKTHNRS HSWYRTDPSM LELIFHRRML EYPCLTEDPK 120 TANAVYLPYY AAFDSLRYLY GPEYNSSEQH GVHLFHFLTK ENHPEIWNRH SGHDHFLVMA 180 RPAWDFAQPL DNDPHLWGTS FLELPHFFNV TALTLESRAW PWQEHAVPYP TSFHPPNLAL 240 LDSWIQRVRR SKRSSLALFA GGGGFSATPN IRRSIRMECD NDNNSSNVNG NSFGYEKLCE 300 TVDCSNGVCE HDPIRFMKPM LGANFCLQPP GDTPTRKSTF DAILAGCIPV FFEDLSAKSQ 360 YSWHLPENEF EGFSVTIPKE DVVFKGLKIF DVLQRIPRAR VRRMREKVLE LIPRVVYRKH 420 NSSPGLRNKK DAFDLTIDGT LNKIRSRLQE LDLVL* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-42 | 86 | 383 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 12 | 448 | 7 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 41 | 453 | 32 | 443 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 36 | 448 | 23 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 18 | 453 | 11 | 437 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 8 | 449 | 5 | 450 | catalytic, putative [Ricinus communis] |