| Basic Information | |
|---|---|
| Species | Medicago truncatula |
| Cazyme ID | Medtr4g127310.1 |
| Family | GH47 |
| Protein Properties | Length: 443 Molecular Weight: 50567.1 Isoelectric Point: 4.8622 |
| Chromosome | Chromosome/Scaffold: 4 Start: 44224200 End: 44229299 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GH47 | 4 | 409 | 0 |
| VDSFGGLGATLVDSLDTLFIMGLDTQFKRAREWIEKSLYFNKDLEVSVFETTIRVLGGLLSAYDLSGDEVFLEKARDLADRLLPAWNTPSGIPYNRINLA YGNTDNPKWTRGNSILADSGSEQLEFIALSQRTKDPKYQEKAEKVIKELRKRFPEDGLLPIYINPLTGDKSAGAITFGAMGDSFYEYLLKAWIQGNKTET VKFYREMWETSMKGLQSLIKKSTPSSFVYISEKLGNSLIDKMDELACFVPGMLALGSSGYGPGEDDKCMALAEELAWTCYNFYQSTPTKLAGENYYFRKD EDMNVGTSWNIQRPETIESLFYLWRFTRNKTYQEWGWNIFQAFEKNSRTETGYVGLRDVNTGDKDDMMQSFFLAETLKYLYLLFSPPSVISLDEWVFNTE AHPLRI | |||
| Full Sequence |
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| Protein Sequence Length: 443 Download |
| MTGVDSFGGL GATLVDSLDT LFIMGLDTQF KRAREWIEKS LYFNKDLEVS VFETTIRVLG 60 GLLSAYDLSG DEVFLEKARD LADRLLPAWN TPSGIPYNRI NLAYGNTDNP KWTRGNSILA 120 DSGSEQLEFI ALSQRTKDPK YQEKAEKVIK ELRKRFPEDG LLPIYINPLT GDKSAGAITF 180 GAMGDSFYEY LLKAWIQGNK TETVKFYREM WETSMKGLQS LIKKSTPSSF VYISEKLGNS 240 LIDKMDELAC FVPGMLALGS SGYGPGEDDK CMALAEELAW TCYNFYQSTP TKLAGENYYF 300 RKDEDMNVGT SWNIQRPETI ESLFYLWRFT RNKTYQEWGW NIFQAFEKNS RTETGYVGLR 360 DVNTGDKDDM MQSFFLAETL KYLYLLFSPP SVISLDEWVF NTEAHPLRIV TRNSHEEGQS 420 IDPEEKIPHH LHGRKEGRID YK* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03897 | lanti_2_LanM | 0.003 | 58 | 160 | 114 | + type 2 lantibiotic biosynthesis protein LanM. Members of this family are known generally as LanM, a multifunctional enzyme of lantibiotic biosynthesis. This catalysis by LanM distinguishes the type 2 lantibiotics, such as mersacidin, cinnamycin, and lichenicidin, from LanBC-produced type 1 lantibiotics such as nisin and subtilin. The N-terminal domain contains regions associated with Ser and Thr dehydration. The C-terminal region contains a pfam05147 domain, which catalyzes the formation of the lanthionine bridge [Cellular processes, Toxin production and resistance]. | ||
| COG1331 | COG1331 | 0.0004 | 57 | 150 | 94 | + Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones] | ||
| PTZ00470 | PTZ00470 | 1.0e-177 | 7 | 409 | 414 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 0 | 2 | 409 | 427 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI17906.1 | 0 | 3 | 417 | 162 | 576 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI18472.1 | 0 | 3 | 438 | 135 | 571 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263484.1 | 0 | 3 | 417 | 25 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325257.1 | 0 | 3 | 441 | 132 | 571 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519409.1 | 0 | 3 | 439 | 122 | 555 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1fo3_A | 0 | 9 | 411 | 47 | 458 | A Chain A, Crystal Structure Of The Nasturtium Seedling Mutant Xyloglucanase Isoform Nxg1-Delta-Yniig |
| PDB | 1fo2_A | 0 | 9 | 411 | 47 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1fmi_A | 0 | 9 | 411 | 47 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1x9d_A | 0 | 9 | 411 | 125 | 536 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| PDB | 1nxc_A | 0 | 7 | 426 | 58 | 478 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CU615093 | 322 | 118 | 439 | 0 |
| DY974119 | 307 | 39 | 345 | 0 |
| EH768908 | 273 | 140 | 412 | 0 |
| GO877285 | 344 | 26 | 369 | 0 |
| EH734230 | 273 | 115 | 387 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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