Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr5g011020.1 |
Family | AA3 |
Protein Properties | Length: 581 Molecular Weight: 63592.5 Isoelectric Point: 7.9689 |
Chromosome | Chromosome/Scaffold: 5 Start: 2846622 End: 2851422 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 45 | 572 | 0 |
ISFYDYIIIGGGTAGCPLAATLSKNHRVLVLERGGSPYGNPNITNLSAFGVALSDPSPSSPAQRFISEDGVINSRARVLGGGSCLNAGFYTRASPRYVSE AEWDEKLVDESYKWVERVVAFQPPMRQWQSAVRDGLLEVGVLPYNGFTYDHIHGTKVGGTIFDHNGHRHTAADLLEYANTNTITLLLHATVHRILFTKSK GGLSSKPIAHGVLYKDARGTEHRAYLNHGTKNEIIVSAGALGSPQLLMLSGIGAAHHLKQHNISVVLHQPFVGQGMSDNPMNSVYVPSPSPVEVSLISVV GITSFGSYIEAASGATFTGSQRDFGMFSPEIGQFSKLPPKQRTPEAIAKAIERMESLDQEAFRGGFILEKILGPISTGHLELRNTDPNENPLVTFNYFQD PRDLERCIQGMNTIEKIIDSKAFSPFKYTNMSVSMLLNMTANSPVNLLPKHTNTSMSLEQFCRDTVMTIWHYHGGCQVGRVVDSDYKVAGVHALRVIDGS TFNHSPGTNPQATVMMLGRYMGVKILRE |
Full Sequence |
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Protein Sequence Length: 581 Download |
MSVLLWRLIL LFLVGIVFSP KHCVSIKDTG RKYSFMQDAT SAPIISFYDY IIIGGGTAGC 60 PLAATLSKNH RVLVLERGGS PYGNPNITNL SAFGVALSDP SPSSPAQRFI SEDGVINSRA 120 RVLGGGSCLN AGFYTRASPR YVSEAEWDEK LVDESYKWVE RVVAFQPPMR QWQSAVRDGL 180 LEVGVLPYNG FTYDHIHGTK VGGTIFDHNG HRHTAADLLE YANTNTITLL LHATVHRILF 240 TKSKGGLSSK PIAHGVLYKD ARGTEHRAYL NHGTKNEIIV SAGALGSPQL LMLSGIGAAH 300 HLKQHNISVV LHQPFVGQGM SDNPMNSVYV PSPSPVEVSL ISVVGITSFG SYIEAASGAT 360 FTGSQRDFGM FSPEIGQFSK LPPKQRTPEA IAKAIERMES LDQEAFRGGF ILEKILGPIS 420 TGHLELRNTD PNENPLVTFN YFQDPRDLER CIQGMNTIEK IIDSKAFSPF KYTNMSVSML 480 LNMTANSPVN LLPKHTNTSM SLEQFCRDTV MTIWHYHGGC QVGRVVDSDY KVAGVHALRV 540 IDGSTFNHSP GTNPQATVMM LGRYMGVKIL RERFADDETT * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR03970 | Rv0697 | 2.0e-23 | 49 | 324 | 308 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
pfam05199 | GMC_oxred_C | 8.0e-25 | 418 | 562 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR01810 | betA | 2.0e-31 | 49 | 562 | 569 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 2.0e-45 | 48 | 573 | 570 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 18 | 573 | 561 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 22 | 577 | 21 | 575 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_001053612.1 | 0 | 33 | 577 | 34 | 584 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002282510.1 | 0 | 36 | 577 | 1 | 541 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002298074.1 | 0 | 1 | 578 | 1 | 574 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002509694.1 | 0 | 3 | 579 | 6 | 547 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ju2_B | 0 | 34 | 577 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 1ju2_A | 0 | 34 | 577 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_B | 0 | 34 | 577 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_A | 0 | 34 | 577 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdn_B | 0 | 34 | 577 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |