Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr5g055350.1 |
Family | GT47 |
Protein Properties | Length: 448 Molecular Weight: 52200.2 Isoelectric Point: 8.19 |
Chromosome | Chromosome/Scaffold: 5 Start: 22252119 End: 22253462 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 55 | 393 | 0 |
QYIYVYDLPSRFNDDLLKGCNTLIKWENMCPYLSNLGLGPKIIEESNETVISKKNWYATHQFSLEVIFHNIMKDYKCLTNDSSLASAIYVPYYAGLDVGR YLWGGFNISIRDESPNQLVKWLAQQSQWKRMYGKDHFMVGGRVGYDFRRGSDKDEDWGTKLMFLPEASNITILLIESCADKEFPLYENEFAIPYPTYFHP SNDDEIFEWQRKMRNRKREYLFSFVGAPRPNLTSSIRNELIDHCQSSKSCKLVGNHFGDPVHVLDVFQKSVFCLQPPGDSFTRRSTFDSILAGCIPVFFH PHSAYKQYMWHFPKNNSSYSVFIPETDVKRKRVMINETL |
Full Sequence |
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Protein Sequence Length: 448 Download |
MNMLMLKKSL VKHWFVIFIS PFILCVSCLI LSKYFMKGVS PTFHAPKKLD PCLGQYIYVY 60 DLPSRFNDDL LKGCNTLIKW ENMCPYLSNL GLGPKIIEES NETVISKKNW YATHQFSLEV 120 IFHNIMKDYK CLTNDSSLAS AIYVPYYAGL DVGRYLWGGF NISIRDESPN QLVKWLAQQS 180 QWKRMYGKDH FMVGGRVGYD FRRGSDKDED WGTKLMFLPE ASNITILLIE SCADKEFPLY 240 ENEFAIPYPT YFHPSNDDEI FEWQRKMRNR KREYLFSFVG APRPNLTSSI RNELIDHCQS 300 SKSCKLVGNH FGDPVHVLDV FQKSVFCLQP PGDSFTRRST FDSILAGCIP VFFHPHSAYK 360 QYMWHFPKNN SSYSVFIPET DVKRKRVMIN ETLFNVQESE VLEMRDEVIR LIPKIVYRYP 420 SSRLETLDDA FDVAVKGVLQ RIEEMKR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-65 | 51 | 382 | 342 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002280815.1 | 0 | 50 | 447 | 91 | 485 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002321098.1 | 0 | 20 | 447 | 16 | 443 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518606.1 | 0 | 50 | 447 | 74 | 465 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002518609.1 | 0 | 6 | 447 | 1 | 468 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 50 | 447 | 100 | 499 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |