Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr7g087100.1 |
Family | GT47 |
Protein Properties | Length: 511 Molecular Weight: 58998.3 Isoelectric Point: 9.9344 |
Chromosome | Chromosome/Scaffold: 7 Start: 26558218 End: 26560835 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 113 | 432 | 0 |
NAVLKVFMYDLPPEFHFGLLDWKGDEKTKNVWPDMKTKIPHYPGGLNLQHSIEYWLTLDILASELPEIYPARIVTRVRNSTEADVIFVPFFSSLTYNRHS KTGPHERRSRNKVLQEKLVRYLMNQEEWKRSGGRDHLILAHHPNSMLDARMKLWPATFILSDFGRYPPNIANVDKDVIAPYKHVIASYVDDQSTFDSRKT LLYFQGAIYRKDGGYARQELFYLLKEEKDVHFSFGSVQKGGVRNATNGMRSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDVLDYSKFCV FVRTRDAVKKKYLINFIRSI |
Full Sequence |
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Protein Sequence Length: 511 Download |
MAEKNTSAIK VVSRKSLWFF FTTTTLFFIM SWLFVLRSTR SDSTPATISQ LLSTTSNDGS 60 DLVTSQSQNS ESSFSNRAIL VNTETKTPET PKCITETTTI SNNDTKSNNN KSNAVLKVFM 120 YDLPPEFHFG LLDWKGDEKT KNVWPDMKTK IPHYPGGLNL QHSIEYWLTL DILASELPEI 180 YPARIVTRVR NSTEADVIFV PFFSSLTYNR HSKTGPHERR SRNKVLQEKL VRYLMNQEEW 240 KRSGGRDHLI LAHHPNSMLD ARMKLWPATF ILSDFGRYPP NIANVDKDVI APYKHVIASY 300 VDDQSTFDSR KTLLYFQGAI YRKDGGYARQ ELFYLLKEEK DVHFSFGSVQ KGGVRNATNG 360 MRSSKFCLNI AGDTPSSNRL FDAIASHCVP VIISDEIELP YEDVLDYSKF CVFVRTRDAV 420 KKKYLINFIR SIGKDEWTRM WNRLKEVEKF FEFQFPSKEG DAVEMIWQAV SRKVPFMKLK 480 TNRSRRFFRA LYGNNKYKGH KSIHAPPNFW * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-57 | 116 | 432 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 1 | 510 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | XP_002268382.1 | 0 | 1 | 510 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 1 | 487 | 3 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 103 | 510 | 58 | 463 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 1 | 495 | 1 | 486 | catalytic, putative [Ricinus communis] |