Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr8g023490.1 |
Family | GT68 |
Protein Properties | Length: 543 Molecular Weight: 62217.4 Isoelectric Point: 7.3793 |
Chromosome | Chromosome/Scaffold: 8 Start: 6163241 End: 6166825 |
Description | O-fucosyltransferase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT68 | 222 | 517 | 0 |
LNRVLVIPSSKVDYQYDRVVDIDHINKCLGKKVVMSFDEFSNVKKGHLHIDKFLCYFALPQPCYLDDERLKKLDGLGLGMSKPKAVWEDEDTRNPKKKTV QDVMDKFSYDDDVMAIGDVFYAKVEHEWVMQPGGPIAHQCKTLIEPNRLILLTAQRFIQTFLGRNFIALHFRRHGFLKFCNAKKPSCFFPIPQAADCILR VIERADAPIIYLSTDAAESETGLLQSLIVLNGKSVPLVIRPARNSAEKWDALLYRHHIEGDSQVEAMLDKTICAMSSVFIGAPGSTFTEDILRLRK |
Full Sequence |
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Protein Sequence Length: 543 Download |
MDSSSDEDDD HHNLIHQPST KPRTPPSTFN VEDLNSRFRR VNFTFQKKHY ILAILLLLLL 60 LFLFFSVPNL RRYFTTSFTS DSITDRMKES ELRAIYLLRQ QQQRLSTVFN SSDQNQNPNP 120 KLIEDLKSAL FKQISINNEI QQILLNPHRT GNVIDPEFNF GNSNFNVGNY DRCRTVDQSL 180 SKRKTIEWNP KKDKFLVAIC VSGQMSNHLI CLEKHMFFAA ILNRVLVIPS SKVDYQYDRV 240 VDIDHINKCL GKKVVMSFDE FSNVKKGHLH IDKFLCYFAL PQPCYLDDER LKKLDGLGLG 300 MSKPKAVWED EDTRNPKKKT VQDVMDKFSY DDDVMAIGDV FYAKVEHEWV MQPGGPIAHQ 360 CKTLIEPNRL ILLTAQRFIQ TFLGRNFIAL HFRRHGFLKF CNAKKPSCFF PIPQAADCIL 420 RVIERADAPI IYLSTDAAES ETGLLQSLIV LNGKSVPLVI RPARNSAEKW DALLYRHHIE 480 GDSQVEAMLD KTICAMSSVF IGAPGSTFTE DILRLRKDWG SASLCDEYLC HGEEPNIVAE 540 NE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd11548 | NodZ_like | 0.0007 | 362 | 517 | 160 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
pfam10250 | O-FucT | 0.0001 | 218 | 509 | 337 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
cd11296 | O-FucT_like | 5.0e-5 | 195 | 238 | 44 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11298 | O-FucT-2 | 7.0e-7 | 383 | 509 | 127 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 2.0e-17 | 358 | 516 | 169 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD50008.1 | 0 | 3 | 542 | 4 | 594 | AC007651_3 Hypothetical Protein [Arabidopsis thaliana] |
RefSeq | NP_173170.2 | 0 | 3 | 542 | 4 | 564 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_199853.1 | 0 | 3 | 542 | 4 | 566 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002264087.1 | 0 | 4 | 542 | 5 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303337.1 | 0 | 69 | 542 | 51 | 527 | predicted protein [Populus trichocarpa] |