| Basic Information | |
|---|---|
| Species | Medicago truncatula |
| Cazyme ID | Medtr8g074330.1 |
| Family | GH19 |
| Protein Properties | Length: 630 Molecular Weight: 67824.6 Isoelectric Point: 7.6993 |
| Chromosome | Chromosome/Scaffold: 8 Start: 19892361 End: 19899338 |
| Description | basic chitinase |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 80 | 313 | 0 |
| VGSIIPSSLFDQMLKYRNDQRCAGHGFYTYDGFIAAARSFNGFGTTGDDATRKKELAAFLAQTSHETTGGWPSAPDGPYAWGYCFVTEKDAQGDFCSPGD WPCAPGKRYYGRGPIQLTHNYNYGQAGKAINEDLINNPDLVSTNPTVSFKTAIWFWMTPQANKPSSHDVITGRWTPSAADSSAGRVPGYGVITNIINGGL ECGHGQDPKVEDRVGFYRRYCQILGVNPGNNLDC | |||
| GH19 | 403 | 622 | 0 |
| GRLVPSFLFDQMLKYRNDARCPGHGFYTYDGFIAATRSFNGFGTTGDDTTRKRELAAFLAQTSHETTGGWSSAPDGPYAWGYCFVNERNAQEKRYYGRGP IQLTHDYNYGQAGKAINQDLINNPDLVSTNPTVSFKTAIWFWMTPQGNKPSSHDVIIGRWTPSGADRSAGRVPGYGVITNIINGGLECGHGQDARVNDRI GFYRRYCQILGVSPGDNLDC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 630 Download |
| MANTNLSCLI LCLLPLFLVA KAEQCGSQAN GALCPNGLCC SKFGFCGNTD QYCGDGCQSQ 60 CKSSPTPNPP TPSTGGGGDV GSIIPSSLFD QMLKYRNDQR CAGHGFYTYD GFIAAARSFN 120 GFGTTGDDAT RKKELAAFLA QTSHETTGGW PSAPDGPYAW GYCFVTEKDA QGDFCSPGDW 180 PCAPGKRYYG RGPIQLTHNY NYGQAGKAIN EDLINNPDLV STNPTVSFKT AIWFWMTPQA 240 NKPSSHDVIT GRWTPSAADS SAGRVPGYGV ITNIINGGLE CGHGQDPKVE DRVGFYRRYC 300 QILGVNPGNN LDCNNQRPFV RNLTKLSCLI LCLLPLFLGS KAEQCGSQAN RAVCPNGLCC 360 SKFGWCGTTD QYCGAGCQSQ CRSSSTPTPS TPTPGTGGGG DVGRLVPSFL FDQMLKYRND 420 ARCPGHGFYT YDGFIAATRS FNGFGTTGDD TTRKRELAAF LAQTSHETTG GWSSAPDGPY 480 AWGYCFVNER NAQEKRYYGR GPIQLTHDYN YGQAGKAINQ DLINNPDLVS TNPTVSFKTA 540 IWFWMTPQGN KPSSHDVIIG RWTPSGADRS AGRVPGYGVI TNIINGGLEC GHGQDARVND 600 RIGFYRRYCQ ILGVSPGDNL DCNNQRSFA* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00442 | lysozyme_like | 3.0e-18 | 136 | 275 | 140 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| cd00325 | chitinase_glyco_hydro_19 | 2.0e-122 | 406 | 622 | 230 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 4.0e-129 | 405 | 622 | 232 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 5.0e-136 | 88 | 313 | 226 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 8.0e-145 | 88 | 313 | 227 | + Chitinase class I. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAP03087.1 | 0 | 1 | 320 | 1 | 326 | class Ib chitinase [Galega orientalis] |
| GenBank | AAP03087.1 | 0 | 320 | 629 | 1 | 326 | class Ib chitinase [Galega orientalis] |
| GenBank | AAP03089.1 | 0 | 1 | 320 | 1 | 331 | class Ib chitinase 2 [Galega orientalis] |
| Swiss-Prot | P36907 | 0 | 5 | 320 | 6 | 320 | CHIX_PEA RecName: Full=Endochitinase; Flags: Precursor |
| Swiss-Prot | P36907 | 0 | 320 | 629 | 1 | 320 | CHIX_PEA RecName: Full=Endochitinase; Flags: Precursor |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3iwr_B | 0 | 23 | 319 | 2 | 298 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 3iwr_B | 0 | 343 | 628 | 2 | 298 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 3iwr_A | 0 | 23 | 319 | 2 | 298 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 3iwr_A | 0 | 343 | 628 | 2 | 298 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 2dkv_A | 0 | 23 | 319 | 2 | 298 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
