Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr8g087930.1 |
Family | GT20 |
Protein Properties | Length: 521 Molecular Weight: 57886.7 Isoelectric Point: 7.6401 |
Chromosome | Chromosome/Scaffold: 8 Start: 24581975 End: 24585803 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 2 | 147 | 0 |
NQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQASKKGVLILSEFAGAAQSLGAGAILVNPWNI TEVAASIGYALDMPADEREKRHQFNFKHVTTHTSQEWAATFVSELN |
Full Sequence |
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Protein Sequence Length: 521 Download |
MNQKLTSQVH EIVGRINGRF GTLTAVPIHH LDRSLDFHAL CALYAVTDVA LVTSLRDGMN 60 LVSYEFVACQ ASKKGVLILS EFAGAAQSLG AGAILVNPWN ITEVAASIGY ALDMPADERE 120 KRHQFNFKHV TTHTSQEWAA TFVSELNDTI VEAQLRTRQV PPLLPNKVAV DCYSKSNNRL 180 IILGFNATLT EPVDPFGRGG QIKELELKVH PDMKEPLKKL SDDPKTTVVV LSGSGRAVLD 240 KNFGEYNMWL AAENGMFLRL TSSEWMTTMP ENLNMDWVDS VKHVFEYFTE RTPRSNFELR 300 ETSVIWNYKY ADVEFGRLQA RDLLQHLWTG PISNASLDVV QGGRSVEVRA VGVSKGAAID 360 RILGEIVHSK GMKEPIDYVL CIGHFLAKDE DVYKFFEPEL PSEVSPMAKA MRSNSCRPSS 420 LPRFSSGKNG PKASQYKKQR SLSNIDRREV DPASGDPWRP TGRDRTSLHE GSSVLDLKGD 480 NYFSCSVARK RSSARYLLKT SQDIVNLLSD LADRSSSPST * |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam00982 | Glyco_transf_20 | 9.0e-76 | 3 | 148 | 146 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. |
pfam02358 | Trehalose_PPase | 4.0e-76 | 209 | 405 | 197 | + Trehalose-phosphatase. This family consist of trehalose-phosphatases EC:3.1.3.12 these enzyme catalyze the de-phosphorylation of trehalose-6-phosphate to trehalose and orthophosphate. The aligned region is present in trehalose-phosphatases and comprises the entire length of the protein it is also found in the C-terminus of trehalose-6-phosphate synthase EC:2.4.1.15 adjacent to the trehalose-6-phosphate synthase domain - pfam00982. It would appear that the two equivalent genes in the E. coli otsBA operon otsA the trehalose-6-phosphate synthase and otsB trehalose-phosphatase (this family) have undergone gene fusion in most eukaryotes. Trehalose is a common disaccharide of bacteria, fungi and invertebrates that appears to play a major role in desiccation tolerance. |
PRK14501 | PRK14501 | 3.0e-103 | 3 | 401 | 401 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
PLN03064 | PLN03064 | 0 | 3 | 517 | 521 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional |
PLN03063 | PLN03063 | 0 | 3 | 512 | 510 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAK44102.2 | 0 | 3 | 518 | 26 | 554 | AF370287_1 putative trehalose-6-phosphate synthase [Arabidopsis thaliana] |
EMBL | CBI30769.1 | 0 | 2 | 515 | 18 | 484 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_001056058.1 | 0 | 2 | 517 | 1 | 515 | Os05g0518600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002305707.1 | 0 | 3 | 519 | 388 | 899 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522296.1 | 0 | 3 | 516 | 404 | 913 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 4e-26 | 3 | 158 | 308 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 4e-26 | 3 | 158 | 308 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 4e-26 | 3 | 158 | 308 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 4e-26 | 3 | 158 | 308 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 5e-26 | 3 | 158 | 308 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES813375 | 395 | 43 | 429 | 0 |
GO265628 | 302 | 37 | 338 | 0 |
DV705833 | 283 | 115 | 396 | 0 |
CX545499 | 287 | 3 | 288 | 0 |
GE582665 | 283 | 18 | 298 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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