Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | Medtr8g102840.1 |
Family | GT47 |
Protein Properties | Length: 654 Molecular Weight: 75770.9 Isoelectric Point: 10.1626 |
Chromosome | Chromosome/Scaffold: 8 Start: 30043192 End: 30046892 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 321 | 602 | 0 |
TLKVYIYMEGNKPIFHQPILKGLYASEGWFMKLMEENKQFVVKDPAKAHLFYMPFSSRMLEFSVYVRNSHNRTNLRQYLKEYTDKISAKYRYFNRTGGAD HFLVACHDWAPYETRHHMEYCIKALCNSDVTQGFKIGRDVSLPETMVRSVRNPQRDLGGKPPQQRSILAFYAGNMHGYLRSILLKHWKEKDPDMKIFGPM PHGVAHKMNYIEHMKSSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLNWDSFSLILAEKDIPNLKQILLSV |
Full Sequence |
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Protein Sequence Length: 654 Download |
MVLSKLKMEE KTTLRNQRSY GAPEKVEDRK TLRGKKKKKH EVECNNTSVF TTLRLLFLLG 60 ALAVNYLLFQ SILVPYENER APWSSSDFNN AVMVEKVNTP IIEDVGMHNH AKSSLVSELG 120 VDRNDFHILL GKKDVGKNRS LELDNVGGSK KSSIVVLAKE SKVDFLVKPS LEPKRGISTI 180 SQLVKSNTID SREHDGVGFD ASQSSMSLTN RTRLESSPQI KKLPASDKST AANNITVRKM 240 RCNMPPKSRM LIQEMNHLLE RRRTSSRAMK ARWKSKLDME IFAARSEIEH APTVTNDKEL 300 YAPLFRNHSM FKRSYELMEL TLKVYIYMEG NKPIFHQPIL KGLYASEGWF MKLMEENKQF 360 VVKDPAKAHL FYMPFSSRML EFSVYVRNSH NRTNLRQYLK EYTDKISAKY RYFNRTGGAD 420 HFLVACHDWA PYETRHHMEY CIKALCNSDV TQGFKIGRDV SLPETMVRSV RNPQRDLGGK 480 PPQQRSILAF YAGNMHGYLR SILLKHWKEK DPDMKIFGPM PHGVAHKMNY IEHMKSSKYC 540 ICPKGYEVNS PRVVEAIFYE CVPVIISDNF VPPFFEVLNW DSFSLILAEK DIPNLKQILL 600 SVPEEKYLKL QLGVRRVQKH FLWHTKPLKY DLFHMTLHSI WYNRVFQINV RKK* 660 |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 3.0e-66 | 322 | 602 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 54 | 653 | 17 | 715 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 166 | 647 | 925 | 1390 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 240 | 651 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 244 | 651 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 225 | 651 | 251 | 676 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GO328935 | 277 | 251 | 527 | 0 |
EG631332 | 277 | 375 | 651 | 0 |
ES808098 | 345 | 285 | 629 | 0 |
DV712689 | 314 | 229 | 542 | 0 |
EV026079 | 246 | 326 | 571 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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