Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00009677m |
Family | GT47 |
Protein Properties | Length: 426 Molecular Weight: 48645.5 Isoelectric Point: 10.1852 |
Chromosome | Chromosome/Scaffold: 005761 Start: 13138 End: 15788 |
Description | FRA8 homolog |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 73 | 370 | 0 |
PVRIYVYDLPARFNRDWVSADARCARHLFAAEVAVHEALLAYAGRAPRPEDADLFFVPVYVSCNFSTPNGFPSLSHARGLLAEAVHLLRTQMPYWNRSAG ADHVFVASHDFGACFHPMEDVAIADGIPEFLKRSILLQTFGVQGHHVCQEVEHVVIPPHVPPEVAHELPEPEKVRRDIFAFFRGKMEVHPKNISGRFYSK KVRTELLQHYGRNRKFYLKRKRFDNYQSEMARSLFCLCPLGWAPWSPRLVESVLLGCIPVIIADNIRLPFPSVLRWPEISLQVAEKDIASLEMVLDQV |
Full Sequence |
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Protein Sequence Length: 426 Download |
MRDPKPRRSP AAPTLASSGR LRKHSTWLLL LLLWFALSVY LFISSTPPAA APLRRSAFLR 60 SKARALSATT ATPVRIYVYD LPARFNRDWV SADARCARHL FAAEVAVHEA LLAYAGRAPR 120 PEDADLFFVP VYVSCNFSTP NGFPSLSHAR GLLAEAVHLL RTQMPYWNRS AGADHVFVAS 180 HDFGACFHPM EDVAIADGIP EFLKRSILLQ TFGVQGHHVC QEVEHVVIPP HVPPEVAHEL 240 PEPEKVRRDI FAFFRGKMEV HPKNISGRFY SKKVRTELLQ HYGRNRKFYL KRKRFDNYQS 300 EMARSLFCLC PLGWAPWSPR LVESVLLGCI PVIIADNIRL PFPSVLRWPE ISLQVAEKDI 360 ASLEMVLDQV VATNLTRIQR NLWDPMKRKA LVFNRPMEVG DATWQVLREL EILLDQSQRR 420 YRSWR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-56 | 73 | 370 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAN62780.1 | 0 | 69 | 425 | 66 | 448 | Unknown protein [Oryza sativa Japonica Group] |
GenBank | ACN31903.1 | 0 | 1 | 425 | 1 | 427 | unknown [Zea mays] |
RefSeq | NP_001048697.1 | 0 | 69 | 425 | 66 | 426 | Os03g0107900 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_197685.2 | 0 | 32 | 422 | 50 | 460 | F8H (FRA8 HOMOLOG); catalytic [Arabidopsis thaliana] |
RefSeq | XP_002468679.1 | 0 | 1 | 425 | 1 | 428 | hypothetical protein SORBIDRAFT_01g050110 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |