Basic Information | |
---|---|
Species | Panicum virgatum |
Cazyme ID | Pavirv00015202m |
Family | GT47 |
Protein Properties | Length: 430 Molecular Weight: 48682.5 Isoelectric Point: 10.0906 |
Chromosome | Chromosome/Scaffold: 040378 Start: 806 End: 3590 |
Description | FRA8 homolog |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 77 | 373 | 0 |
VRIYVYDLPARFNRDWVAADARCARHLFAAEVAVHEALLAYAGRAARPDDADLFFVPVYVSCNFSTPNGFPSLSHARGLLADAVHLLRTQMPYWNRSAGA DHIFVASHDFGACFHPMEDVAIADGIPEFLKRSILLQTFGVQGHHVCQEVEHVVIPPHVPPEVSHELPEPEKVRRDIFAFFRGKMEVHPKNISGRFYSKK VRTELLQHYGRNRKFYLKRKRFDNYQSEMARSLFCLCPLGWAPWSPRLVESVLLGCIPVIIADNIRLPFPSVLRWPEISLQVAEKDIASLETVLDHV |
Full Sequence |
---|
Protein Sequence Length: 430 Download |
MRGDPKPPPR RSPAAPTLAG RLRKHSTSLL LLLLWFALSL YLFISPTPPA AAPLRRSAFL 60 RSKARALSAT TAGAPPVRIY VYDLPARFNR DWVAADARCA RHLFAAEVAV HEALLAYAGR 120 AARPDDADLF FVPVYVSCNF STPNGFPSLS HARGLLADAV HLLRTQMPYW NRSAGADHIF 180 VASHDFGACF HPMEDVAIAD GIPEFLKRSI LLQTFGVQGH HVCQEVEHVV IPPHVPPEVS 240 HELPEPEKVR RDIFAFFRGK MEVHPKNISG RFYSKKVRTE LLQHYGRNRK FYLKRKRFDN 300 YQSEMARSLF CLCPLGWAPW SPRLVESVLL GCIPVIIADN IRLPFPSVLR WPEISLQVAE 360 KDIASLETVL DHVVATNLTR IQKNLWDPMK RKALVFNRPM EVGDATWQVL RELEILLDQS 420 QRRYVGSWR* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-59 | 75 | 370 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAN62780.1 | 0 | 67 | 429 | 64 | 448 | Unknown protein [Oryza sativa Japonica Group] |
GenBank | ACN31903.1 | 0 | 3 | 429 | 2 | 427 | unknown [Zea mays] |
RefSeq | NP_001048697.1 | 0 | 67 | 429 | 64 | 426 | Os03g0107900 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_197685.2 | 0 | 33 | 423 | 50 | 458 | F8H (FRA8 HOMOLOG); catalytic [Arabidopsis thaliana] |
RefSeq | XP_002468679.1 | 0 | 7 | 429 | 4 | 428 | hypothetical protein SORBIDRAFT_01g050110 [Sorghum bicolor] |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |