Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00019260m |
Family | GT47 |
Protein Properties | Length: 461 Molecular Weight: 51847.3 Isoelectric Point: 8.612 |
Chromosome | Chromosome/Scaffold: 053249 Start: 1975 End: 3899 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 66 | 381 | 0 |
LRVYMYDLPPEFHFGLLDWKPPGFGGGVWPDVRGAVPEYPGGLNLQHSIEYWLTLDLLASEQGAPTPCAAVRVRRHADADVVFVPFFASLSFNRHSRVVP PARDSEDRALQRRLLEFLAARPEWRRTGGRDHVVLAHHPNGMLDARYRLWPCVFVLCDFGRYPPSVANLDKDVIAPYRHVVDNFANDTAGYDDRPTLLYF QGAIYRKDGGSIRQELYYLLKDEKDVHFSFGSVAGNGIEQATQGMRASKFCLNIAGDTPSSNRLFDSIVSHCVPVIISDEIELPFEDVLVYSKFSIIVRG ADAVKKGFLMNLIRGI |
Full Sequence |
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Protein Sequence Length: 461 Download |
MAAAGAAPCR SPLAWLFALA AALFFASWYL LLDSAAAARA YQGLRLGAGG RLPGLGTKCD 60 PARALLRVYM YDLPPEFHFG LLDWKPPGFG GGVWPDVRGA VPEYPGGLNL QHSIEYWLTL 120 DLLASEQGAP TPCAAVRVRR HADADVVFVP FFASLSFNRH SRVVPPARDS EDRALQRRLL 180 EFLAARPEWR RTGGRDHVVL AHHPNGMLDA RYRLWPCVFV LCDFGRYPPS VANLDKDVIA 240 PYRHVVDNFA NDTAGYDDRP TLLYFQGAIY RKDGGSIRQE LYYLLKDEKD VHFSFGSVAG 300 NGIEQATQGM RASKFCLNIA GDTPSSNRLF DSIVSHCVPV IISDEIELPF EDVLVYSKFS 360 IIVRGADAVK KGFLMNLIRG ISREEWTLMW NWLKEVEKHF EYQYPSQTDD AVQMIWKTIA 420 RKVPSIRLKV NRLRRFSRFE TNRTNESPPH SSSWLQNQAP * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-54 | 66 | 381 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACF84601.1 | 0 | 58 | 460 | 60 | 462 | unknown [Zea mays] |
RefSeq | NP_001049980.1 | 0 | 37 | 458 | 48 | 466 | Os03g0324700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001131151.1 | 0 | 70 | 460 | 1 | 391 | hypothetical protein LOC100192459 [Zea mays] |
RefSeq | NP_001136572.1 | 0 | 35 | 459 | 35 | 452 | hypothetical protein LOC100216694 [Zea mays] |
RefSeq | XP_002467934.1 | 0 | 42 | 460 | 48 | 462 | hypothetical protein SORBIDRAFT_01g036720 [Sorghum bicolor] |