Basic Information | |
---|---|
Species | Panicum virgatum |
Cazyme ID | Pavirv00020030m |
Family | GT13 |
Protein Properties | Length: 432 Molecular Weight: 49789 Isoelectric Point: 7.648 |
Chromosome | Chromosome/Scaffold: 028310 Start: 300 End: 7431 |
Description | alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, putative |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT13 | 22 | 426 | 0 |
IQVRLFATQSHYADRLAEAEKSENQCTSQLKSLIDQVSMQQEKIVALEEMKIRQDEERAHLKILIQDLEKRSVQKLLNKNVVPVAAVVIMACNRPDYLER TVESILKYQTSVASKFPLFISQDGTNGAVKKKALDYKQITYMQHLNLEPVRTERPGELTAYYKIAKHYKWALDELFIKHNFARVIILEDDMEIAPDFFDY FEAAAKLLDNDKTIMAVSSWNDNGQKQFVNDPKALYRSDFFPGLGWMLTKSTWLELSPKLKEIHGNRQFIRPEICRTYNFGKHGSSLGQFFEQYLEPIKL NDVHIDWNSEDLSYLGEDKFSTKFGKEVASATPLHGSDAVLKAHSMAADVRIQYDDQEDFERIARQFGIFEEWKDGIPRTAYKGVVVFRYKSSRRRIFLV SPDSL |
Full Sequence |
---|
Protein Sequence Length: 432 Download |
MARSPCDLRL LLLAATVAFI YIQVRLFATQ SHYADRLAEA EKSENQCTSQ LKSLIDQVSM 60 QQEKIVALEE MKIRQDEERA HLKILIQDLE KRSVQKLLNK NVVPVAAVVI MACNRPDYLE 120 RTVESILKYQ TSVASKFPLF ISQDGTNGAV KKKALDYKQI TYMQHLNLEP VRTERPGELT 180 AYYKIAKHYK WALDELFIKH NFARVIILED DMEIAPDFFD YFEAAAKLLD NDKTIMAVSS 240 WNDNGQKQFV NDPKALYRSD FFPGLGWMLT KSTWLELSPK LKEIHGNRQF IRPEICRTYN 300 FGKHGSSLGQ FFEQYLEPIK LNDVHIDWNS EDLSYLGEDK FSTKFGKEVA SATPLHGSDA 360 VLKAHSMAAD VRIQYDDQED FERIARQFGI FEEWKDGIPR TAYKGVVVFR YKSSRRRIFL 420 VSPDSLRQLG V* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00761 | Glyco_tranf_GTA_type | 0.004 | 108 | 241 | 138 | + Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities. | ||
cd06532 | Glyco_transf_25 | 0.002 | 149 | 237 | 96 | + Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis. | ||
cd02514 | GT13_GLCNAC-TI | 5.0e-155 | 105 | 425 | 337 | + GT13_GLCNAC-TI is involved in an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (GLCNAC-T I , GNT-I) transfers N-acetyl-D-glucosamine from UDP to high-mannose glycoprotein N-oligosaccharide, an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. The enzyme is an integral membrane protein localized to the Golgi apparatus. The catalytic domain is located at the C-terminus. These proteins are members of the glycosy transferase family 13. | ||
pfam03071 | GNT-I | 0 | 15 | 430 | 433 | + GNT-I family. Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (GNT-I, GLCNAC-T I) EC:2.4.1.101 transfers N-acetyl-D-glucosamine from UDP to high-mannose glycoprotein N-oligosaccharide. This is an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. The enzyme is an integral membrane protein localised to the Golgi apparatus, and is probably distributed in all tissues. The catalytic domain is located at the C-terminus. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0000139 | Golgi membrane |
GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity |
GO:0006487 | protein N-linked glycosylation |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACF83572.1 | 0 | 1 | 431 | 1 | 425 | unknown [Zea mays] |
GenBank | ACG37957.1 | 0 | 1 | 431 | 1 | 442 | N-acetylglucosaminyltransferase I [Zea mays] |
RefSeq | NP_001048631.1 | 0 | 1 | 431 | 1 | 442 | Os02g0832800 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001142278.1 | 0 | 1 | 431 | 1 | 442 | hypothetical protein LOC100274447 [Zea mays] |
RefSeq | XP_002441861.1 | 0 | 1 | 431 | 1 | 442 | hypothetical protein SORBIDRAFT_08g003660 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1foa_A | 0 | 105 | 425 | 8 | 339 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 1fo9_A | 0 | 105 | 425 | 8 | 339 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 1fo8_A | 0 | 105 | 425 | 3 | 334 | A Chain A, Crystal Structure Of N-Acetylglucosaminyltransferase I |
PDB | 2apc_A | 0 | 105 | 425 | 2 | 333 | A Chain A, Crystal Structure Of N-Acetylglucosaminyltransferase I |
PDB | 2am5_A | 0 | 105 | 425 | 2 | 333 | A Chain A, Crystal Structure Of N-Acetylglucosaminyltransferase I |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
GO802527 | 323 | 29 | 339 | 0 |
GO865783 | 329 | 8 | 325 | 0 |
GO802714 | 312 | 29 | 328 | 0 |
GT047470 | 295 | 121 | 404 | 0 |
GO870530 | 318 | 8 | 313 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|