Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00022063m |
Family | GT47 |
Protein Properties | Length: 463 Molecular Weight: 51719.1 Isoelectric Point: 8.9264 |
Chromosome | Chromosome/Scaffold: 014322 Start: 6704 End: 8634 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 68 | 383 | 0 |
LRVYMYDLPPEFHFGLLDGAPPGFGGGVWPDVRATVPEYPGGLNLQHSVEYWLTLDLLASEQGAPTPCAAVRVRRHADADVVLVPFFASLSFNRHSRVVP PARGSEDRALQRRLLQFLAARPEWRRTGGRDHVVLAHHPNGMLDARYRLWPCVFVLCDFGRYPPSVANLDKDVIAPYRHLVDNFANDTAGYHDRPTLLYF QGAIYRKDGGSIRQELYYLLKDEKDVHFSFGSVAGNGIEQATQGMRASKFCLNIAGDTPSSNRLFDSIVSHCVPVIISDEIELPFEDVLVYSKFSVIVRG ADAVKKGFLMNLIRGV |
Full Sequence |
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Protein Sequence Length: 463 Download |
MAAAAASCRS PLAWLFALAA ALFFASWYLL LDSAAGPAAA YQGLRLAAGA RGRLPGPGTK 60 CDPARALLRV YMYDLPPEFH FGLLDGAPPG FGGGVWPDVR ATVPEYPGGL NLQHSVEYWL 120 TLDLLASEQG APTPCAAVRV RRHADADVVL VPFFASLSFN RHSRVVPPAR GSEDRALQRR 180 LLQFLAARPE WRRTGGRDHV VLAHHPNGML DARYRLWPCV FVLCDFGRYP PSVANLDKDV 240 IAPYRHLVDN FANDTAGYHD RPTLLYFQGA IYRKDGGSIR QELYYLLKDE KDVHFSFGSV 300 AGNGIEQATQ GMRASKFCLN IAGDTPSSNR LFDSIVSHCV PVIISDEIEL PFEDVLVYSK 360 FSVIVRGADA VKKGFLMNLI RGVSREEWTL MWNRLKEVEK HFEYQYPSQT DDAVQMIWKT 420 IARKVPSIRL KINRLRRFSR FETNKTDESP PHSSSWLQNQ AP* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 2.0e-48 | 68 | 383 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACF84601.1 | 0 | 60 | 462 | 60 | 462 | unknown [Zea mays] |
RefSeq | NP_001049980.1 | 0 | 38 | 460 | 48 | 466 | Os03g0324700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001131151.1 | 0 | 72 | 462 | 1 | 391 | hypothetical protein LOC100192459 [Zea mays] |
RefSeq | NP_001136572.1 | 0 | 34 | 461 | 31 | 452 | hypothetical protein LOC100216694 [Zea mays] |
RefSeq | XP_002467934.1 | 0 | 42 | 462 | 48 | 462 | hypothetical protein SORBIDRAFT_01g036720 [Sorghum bicolor] |