| Basic Information | |
|---|---|
| Species | Panicum virgatum |
| Cazyme ID | Pavirv00026596m |
| Family | GH89 |
| Protein Properties | Length: 591 Molecular Weight: 67801.3 Isoelectric Point: 5.1346 |
| Chromosome | Chromosome/Scaffold: 025336 Start: 856 End: 6789 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH89 | 1 | 237 | 0 |
| WGGPLPQTWLDDQLALQKKILSRMYAFGMFPVLPAFSGNIPAALKAKFPSAKVTHLGNWFTVDSNPRWCCTYLLDASDPLFIEIGKLFIEEQIRALCLVM SDILRDSNIQIMLLCDDIWLFSYSTSTCHFCNTGSLGSFVLPDHIFGELNTPPLSDPNYISSLGAATFRGMQSGDDDAVWLMQGWLFTYDPFWEPPQMKA LLHSVPVGRMIVLDLYAEVKPVWINSDQFYGVPYIWK | |||
| GH89 | 238 | 567 | 0 |
| VGVGMSMEGIEQNPIVYDLMSEMAFHHEQVDLQVWVETYPTRRYGKPVKGLQDAWWILYQTLYNCTDGKNDKNRDVIVAFPDVEPFVIQTQGLHMSYGKL YSTRSPKNYEKGTSNDAYEHPHMWYNTSVVVHALELFLQYGDEVSDSNTFRYDLVDLTRQVLAKYANDVFIKIIKSYKSNSTNQMITLCQHFLGLVNDLD TLLASHEGFLLGPWLENAKGLARDQKQEIQYEWNARTQITMWFDNTETKASLLRDYANKYWCGLLRDYYGPRAAIYFKHLLQSMKKNEPFALEEWRREWI SLTNNWQSDRKVFATTATGDALNISRSLYM | |||
| Full Sequence |
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| Protein Sequence Length: 591 Download |
| WGGPLPQTWL DDQLALQKKI LSRMYAFGMF PVLPAFSGNI PAALKAKFPS AKVTHLGNWF 60 TVDSNPRWCC TYLLDASDPL FIEIGKLFIE EQIRALCLVM SDILRDSNIQ IMLLCDDIWL 120 FSYSTSTCHF CNTGSLGSFV LPDHIFGELN TPPLSDPNYI SSLGAATFRG MQSGDDDAVW 180 LMQGWLFTYD PFWEPPQMKA LLHSVPVGRM IVLDLYAEVK PVWINSDQFY GVPYIWKVGV 240 GMSMEGIEQN PIVYDLMSEM AFHHEQVDLQ VWVETYPTRR YGKPVKGLQD AWWILYQTLY 300 NCTDGKNDKN RDVIVAFPDV EPFVIQTQGL HMSYGKLYST RSPKNYEKGT SNDAYEHPHM 360 WYNTSVVVHA LELFLQYGDE VSDSNTFRYD LVDLTRQVLA KYANDVFIKI IKSYKSNSTN 420 QMITLCQHFL GLVNDLDTLL ASHEGFLLGP WLENAKGLAR DQKQEIQYEW NARTQITMWF 480 DNTETKASLL RDYANKYWCG LLRDYYGPRA AIYFKHLLQS MKKNEPFALE EWRREWISLT 540 NNWQSDRKVF ATTATGDALN ISRSLYMKYF GNVDLVELEG TSSPGESASL * 600 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05089 | NAGLU | 1.0e-90 | 1 | 266 | 299 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| pfam12972 | NAGLU_C | 2.0e-97 | 272 | 569 | 298 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAE04506.2 | 0 | 1 | 580 | 243 | 817 | OSJNBb0059K02.16 [Oryza sativa (japonica cultivar-group)] |
| GenBank | EEC78143.1 | 0 | 1 | 580 | 243 | 817 | hypothetical protein OsI_17702 [Oryza sativa Indica Group] |
| GenBank | EEE61812.1 | 0 | 1 | 580 | 543 | 1117 | hypothetical protein OsJ_16433 [Oryza sativa Japonica Group] |
| RefSeq | NP_001054095.1 | 0 | 150 | 580 | 55 | 519 | Os04g0650900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002280399.1 | 0 | 1 | 578 | 241 | 813 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 1 | 582 | 350 | 889 | A Chain A, Crystal Structure Of A Putative Metallopeptidase (Sama_0725) From Shewanella Amazonensis Sb2b At 2.00 A Resolution |
| PDB | 2vcb_A | 0 | 1 | 582 | 350 | 889 | A Chain A, Crystal Structure Of A Putative Metallopeptidase (Sama_0725) From Shewanella Amazonensis Sb2b At 2.00 A Resolution |
| PDB | 2vca_A | 0 | 1 | 582 | 350 | 889 | A Chain A, Crystal Structure Of A Putative Metallopeptidase (Sama_0725) From Shewanella Amazonensis Sb2b At 2.00 A Resolution |
| PDB | 2vc9_A | 0 | 1 | 582 | 350 | 889 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 1 | 582 | 373 | 912 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| GT049437 | 304 | 279 | 581 | 0 |
| GT044006 | 304 | 279 | 581 | 0 |
| GD038118 | 232 | 348 | 579 | 0 |
| GT039480 | 316 | 238 | 550 | 0 |
| HO783128 | 420 | 150 | 536 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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