| Basic Information | |
|---|---|
| Species | Panicum virgatum |
| Cazyme ID | Pavirv00031056m |
| Family | GT47 |
| Protein Properties | Length: 323 Molecular Weight: 36222.9 Isoelectric Point: 10.7678 |
| Chromosome | Chromosome/Scaffold: 006355 Start: 748 End: 3871 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 55 | 310 | 1.20512e-43 |
| ADLRIYVYSEDEIQGLRALLRGRDGTVAAATCLKGQWGTQVKIHQLLLKSRFRTFTKDEANLFFVPSYVKCVRMTGALNDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWATFLNRSIILTPEGDRTDKRGTSAFNTWKDIIIPGNVDDSMVKSDARAVQPIPLRKRKYLSNFLGRAQGKAGRLQLVKL AKQYPDKLESPELKLSGPNKLGRIDYFKHLRNAKFCLAPRGESSWTLRFYESFFVV | |||
| Full Sequence |
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| Protein Sequence Length: 323 Download |
| MRHHHACSRA HQVGALLLVA ATFLLTRLFD RLLLDASSPS SPSSPLSAAR PASSADLRIY 60 VYSEDEIQGL RALLRGRDGT VAAATCLKGQ WGTQVKIHQL LLKSRFRTFT KDEANLFFVP 120 SYVKCVRMTG ALNDKEINQT YVKVLSQMPY FRRSGGRDHI FVFPSGAGAH LFRSWATFLN 180 RSIILTPEGD RTDKRGTSAF NTWKDIIIPG NVDDSMVKSD ARAVQPIPLR KRKYLSNFLG 240 RAQGKAGRLQ LVKLAKQYPD KLESPELKLS GPNKLGRIDY FKHLRNAKFC LAPRGESSWT 300 LRFYESFFVV SSPLLLLKEG FM* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-27 | 59 | 308 | 255 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY93033.1 | 0 | 3 | 319 | 5 | 318 | hypothetical protein OsI_14833 [Oryza sativa Indica Group] |
| RefSeq | NP_001131485.1 | 0 | 1 | 319 | 1 | 315 | hypothetical protein LOC100192822 [Zea mays] |
| RefSeq | XP_002300942.1 | 0 | 3 | 316 | 15 | 346 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002458782.1 | 0 | 1 | 319 | 1 | 315 | hypothetical protein SORBIDRAFT_03g040220 [Sorghum bicolor] |
| RefSeq | XP_002526175.1 | 0 | 4 | 316 | 18 | 339 | catalytic, putative [Ricinus communis] |
