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Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00031885m |
Family | CE1 |
Protein Properties | Length: 325 Molecular Weight: 35769.4 Isoelectric Point: 8.223 |
Chromosome | Chromosome/Scaffold: 012803 Start: 3980 End: 10058 |
Description | S-formylglutathione hydrolase |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CE1 | 66 | 318 | 0 |
SATLGCPMTFTVYLPPSPASNVPVLYWLSGLTCTDENFIIKAGAQRAAAAHGIALVAPDTSPRGLNIEGESDSYDFGVGAGFYLNATNEKWKNWRMYDYV VKELPKVLSDHFEQLNISQASISGHSMGGHGALTIYSKNTDKYKSVSAFAPIVNPINCPWGQKAFSNYLGSTKSDWEEYDATCLIKKNSKVSTPILIDQG EDDKFLAEQLLPRNFEEACKAAGVPLILRKQPGYDHSYFFVATFIDDHIAHHA |
Full Sequence |
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Protein Sequence Length: 325 Download |
IISSPSAQRQ SPLTTPHSHS PRLHRTGRRR PGVDPAMAAR PPTTEVELLS TNKMFGGHNL 60 RYRHQSATLG CPMTFTVYLP PSPASNVPVL YWLSGLTCTD ENFIIKAGAQ RAAAAHGIAL 120 VAPDTSPRGL NIEGESDSYD FGVGAGFYLN ATNEKWKNWR MYDYVVKELP KVLSDHFEQL 180 NISQASISGH SMGGHGALTI YSKNTDKYKS VSAFAPIVNP INCPWGQKAF SNYLGSTKSD 240 WEEYDATCLI KKNSKVSTPI LIDQGEDDKF LAEQLLPRNF EEACKAAGVP LILRKQPGYD 300 HSYFFVATFI DDHIAHHAQF LKSA* 360 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01738 | DLH | 0.002 | 255 | 304 | 50 | + Dienelactone hydrolase family. | ||
pfam00756 | Esterase | 7.0e-46 | 66 | 316 | 264 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
COG0627 | COG0627 | 3.0e-82 | 46 | 324 | 310 | + Predicted esterase [General function prediction only] | ||
TIGR02821 | fghA_ester_D | 5.0e-125 | 47 | 321 | 277 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
PLN02442 | PLN02442 | 0 | 42 | 323 | 283 | + S-formylglutathione hydrolase |
Gene Ontology | |
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GO Term | Description |
GO:0004091 | carboxylesterase activity |
GO:0006508 | proteolysis |
GO:0008236 | serine-type peptidase activity |
GO:0016023 | cytoplasmic membrane-bounded vesicle |
GO:0018738 | S-formylglutathione hydrolase activity |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACJ11734.1 | 0 | 49 | 322 | 8 | 283 | S-formylglutathione hydrolase [Gossypium hirsutum] |
RefSeq | NP_001045351.1 | 0 | 46 | 324 | 14 | 292 | Os01g0939700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001148438.1 | 0 | 37 | 324 | 1 | 290 | esterase D [Zea mays] |
RefSeq | XP_002284489.1 | 0 | 37 | 321 | 1 | 282 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002456916.1 | 0 | 46 | 324 | 5 | 284 | hypothetical protein SORBIDRAFT_03g045400 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3fcx_B | 0 | 46 | 323 | 3 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
PDB | 3fcx_A | 0 | 46 | 323 | 3 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
PDB | 3s8y_A | 0 | 46 | 323 | 4 | 280 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
PDB | 3i6y_B | 0 | 46 | 323 | 4 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
PDB | 3i6y_A | 0 | 46 | 323 | 4 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
formaldehyde oxidation II (glutathione-dependent) | S-FORMYLGLUTATHIONE-HYDROLASE-RXN | EC-3.1.2.12 | S-formylglutathione hydrolase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EG384989 | 285 | 41 | 325 | 0 |
CT848008 | 280 | 46 | 325 | 0 |
CJ684473 | 272 | 54 | 325 | 0 |
EB665483 | 285 | 12 | 294 | 0 |
FF349243 | 278 | 41 | 318 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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