Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00033421m |
Family | GT47 |
Protein Properties | Length: 375 Molecular Weight: 42721.1 Isoelectric Point: 9.4996 |
Chromosome | Chromosome/Scaffold: 0267423 Start: 82 End: 1453 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 40 | 322 | 0 |
KLFKVYVYEEGEPPVFHDGPCRSIYSTEGRFIYSMEMESRLRTRDPDRAHAFFLPFSVVKMVKMIYEPNSHDMGPLKRTISDYIGVLSTKYPYWNRSLGA DHFMLSCHDWGPYVSSANGHLFGNSIRVLCNANTSEGFNPAKDVSLPEINLRSDVVDRQVGGPSASRRPILAFFAGGNHGPVRPALLAHWKGKGEPDVQV SEYLPRGVSYSDMMRRSRFCLCPGGYEVASPRLAEAIYLECVPVVVDDGEYALPFADVLNWDAFAVRLRAADIPRLREVLAAV |
Full Sequence |
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Protein Sequence Length: 375 Download |
MEAIKNKDKR PPLSDKDYVP MGPIYRNAYA FHRSYLEMEK LFKVYVYEEG EPPVFHDGPC 60 RSIYSTEGRF IYSMEMESRL RTRDPDRAHA FFLPFSVVKM VKMIYEPNSH DMGPLKRTIS 120 DYIGVLSTKY PYWNRSLGAD HFMLSCHDWG PYVSSANGHL FGNSIRVLCN ANTSEGFNPA 180 KDVSLPEINL RSDVVDRQVG GPSASRRPIL AFFAGGNHGP VRPALLAHWK GKGEPDVQVS 240 EYLPRGVSYS DMMRRSRFCL CPGGYEVASP RLAEAIYLEC VPVVVDDGEY ALPFADVLNW 300 DAFAVRLRAA DIPRLREVLA AVSPRQYIRM QRRVRAVRRH FMVHGGAPRR YDAFHMILHS 360 VWLRRLNVRI AAQG* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-63 | 38 | 322 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 21 | 370 | 59 | 405 | unnamed protein product [Arabidopsis thaliana] |
GenBank | EAZ03045.1 | 0 | 7 | 373 | 232 | 599 | hypothetical protein OsI_25187 [Oryza sativa Indica Group] |
RefSeq | NP_001059081.1 | 0 | 2 | 373 | 232 | 604 | Os07g0188700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002459470.1 | 0 | 1 | 374 | 197 | 582 | hypothetical protein SORBIDRAFT_02g005180 [Sorghum bicolor] |
RefSeq | XP_002528630.1 | 0 | 15 | 370 | 213 | 565 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FE523338 | 294 | 14 | 307 | 0 |
GW864815 | 307 | 54 | 360 | 0 |
CF437544 | 255 | 40 | 294 | 0 |
GW895167 | 299 | 15 | 313 | 0 |
EH772765 | 283 | 40 | 320 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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