Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00039830m |
Family | GT47 |
Protein Properties | Length: 332 Molecular Weight: 37951.4 Isoelectric Point: 9.6637 |
Chromosome | Chromosome/Scaffold: 055049 Start: 82 End: 2572 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 17 | 268 | 0 |
RREAVRVRDPDAAEAFFVPFFSSLSFNVHGRNMTDPDTEADRLLQVELMDILWKSKYWQRSAGRDHVIPMHHPNAFRFLRNLVNASILIVADFGRYTKEL ASLRKDVVAPYVHVVGSFIDDDPPDPFEARHTLLFFRGRTVRKDEGKIRAKLAKILKGKDGVRFENSFATGDGIKISTEGMRSSKFCLHPAGDTPSSCRL FDAIVSHCVPVIVSSRIELPFEDEIDYSEFSLFFSVEEALRPDYLINQLRQI |
Full Sequence |
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Protein Sequence Length: 332 Download |
MASLQDGGGG GGAGSERREA VRVRDPDAAE AFFVPFFSSL SFNVHGRNMT DPDTEADRLL 60 QVELMDILWK SKYWQRSAGR DHVIPMHHPN AFRFLRNLVN ASILIVADFG RYTKELASLR 120 KDVVAPYVHV VGSFIDDDPP DPFEARHTLL FFRGRTVRKD EGKIRAKLAK ILKGKDGVRF 180 ENSFATGDGI KISTEGMRSS KFCLHPAGDT PSSCRLFDAI VSHCVPVIVS SRIELPFEDE 240 IDYSEFSLFF SVEEALRPDY LINQLRQISK KKWVEMWLKL KNISHHYEFQ YPPRKGDAVN 300 MIWRQVRHKI PAVNLAIHRN RRLKIPDWWG Q* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-60 | 21 | 268 | 256 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY77012.1 | 0 | 42 | 330 | 128 | 416 | hypothetical protein OsI_04969 [Oryza sativa Indica Group] |
RefSeq | NP_001045226.1 | 0 | 18 | 330 | 125 | 437 | Os01g0921300 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001152546.1 | 0 | 1 | 330 | 101 | 427 | exostosin-like [Zea mays] |
RefSeq | XP_002456855.1 | 0 | 1 | 330 | 106 | 432 | hypothetical protein SORBIDRAFT_03g044100 [Sorghum bicolor] |
RefSeq | XP_002512333.1 | 0 | 14 | 329 | 116 | 431 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FE645805 | 246 | 43 | 288 | 0 |
FE645470 | 250 | 25 | 274 | 0 |
JG834359 | 236 | 97 | 332 | 0 |
EC955869 | 281 | 27 | 307 | 0 |
FE645470 | 18 | 266 | 283 | 2.7 |
Sequence Alignments (This image is cropped. Click for full image.) |
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