Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00040881m |
Family | GT47 |
Protein Properties | Length: 323 Molecular Weight: 36335.3 Isoelectric Point: 10.2876 |
Chromosome | Chromosome/Scaffold: 0367887 Start: 62 End: 1030 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 21 | 318 | 0 |
CAGRYIYVQELPRRFNADLLRDCRSLSEWTDMCKHVANAGMGPRLTRTGGVLPPTGWYDTNQFTLEVVFHNRMRQYGCLTADASRAAAVYVPYYAGLDVG RHLWGFSNDVRDALAEDLVEWLRSTPAWAAHGGRDHFLVGGRIAWDFRRQDGGGEWGSRLLLLPEARNMTALVLESGGPWHVGDVGVPYPTYFHPSRAAE VASWQRTVRRARRPWLFAFAGARRAGEGGTLRDTVIDQCARSRRCGLLQCGRGRRNDCYAPGNVMRHLRSAAFCLQPPGDSYTRRSAFDAMLAGCVPC |
Full Sequence |
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Protein Sequence Length: 323 Download |
VARRQERQRR AARRAAVADR CAGRYIYVQE LPRRFNADLL RDCRSLSEWT DMCKHVANAG 60 MGPRLTRTGG VLPPTGWYDT NQFTLEVVFH NRMRQYGCLT ADASRAAAVY VPYYAGLDVG 120 RHLWGFSNDV RDALAEDLVE WLRSTPAWAA HGGRDHFLVG GRIAWDFRRQ DGGGEWGSRL 180 LLLPEARNMT ALVLESGGPW HVGDVGVPYP TYFHPSRAAE VASWQRTVRR ARRPWLFAFA 240 GARRAGEGGT LRDTVIDQCA RSRRCGLLQC GRGRRNDCYA PGNVMRHLRS AAFCLQPPGD 300 SYTRRSAFDA MLAGCVPCLH RAR |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-45 | 25 | 317 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA99677.1 | 0 | 21 | 319 | 97 | 409 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
GenBank | EAY83600.1 | 0 | 21 | 319 | 97 | 409 | hypothetical protein OsI_38822 [Oryza sativa Indica Group] |
GenBank | EEE53469.1 | 0 | 21 | 319 | 97 | 370 | hypothetical protein OsJ_36598 [Oryza sativa Japonica Group] |
RefSeq | XP_002442366.1 | 0 | 8 | 319 | 161 | 468 | hypothetical protein SORBIDRAFT_08g018880 [Sorghum bicolor] |
RefSeq | XP_002468517.1 | 0 | 6 | 319 | 126 | 436 | hypothetical protein SORBIDRAFT_01g047270 [Sorghum bicolor] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EG389479 | 236 | 25 | 259 | 0 |
BM407941 | 258 | 38 | 294 | 0 |
GR934411 | 265 | 25 | 288 | 0 |
EY724166 | 237 | 25 | 260 | 0 |
EL456596 | 254 | 67 | 319 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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