Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00041618m |
Family | GT47 |
Protein Properties | Length: 421 Molecular Weight: 46618.6 Isoelectric Point: 7.855 |
Chromosome | Chromosome/Scaffold: 017434 Start: 1555 End: 4600 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 53 | 348 | 0 |
RLKVYVYDLPARYNTALLEKDPRCLTHMFAAEVFVHRSLLSSAVRTLDPEEADWFFVPVYTTCDLTSSGHPMPFDSPRMMRGAIRLVAERWPHWNRSEGA DHFFVTPHDFGACFHFKEEKAVARGILPLLRRATLVQTFGQRRHACLKGGSITVPPYAPPARMEARRLPPGTPRSVFAYFRGLFYDAGNDPEGGRYARGA RASVWENFRSSPVFDISAERPATYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVVIADGIVLPFADAIPWADVGVFVAEEDVPRLDTILTSI |
Full Sequence |
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Protein Sequence Length: 421 Download |
MNMRQVFAIA ILAATAAAVL FLGSEAQEVK QDHHTERISG SAGNVLEDDP VGRLKVYVYD 60 LPARYNTALL EKDPRCLTHM FAAEVFVHRS LLSSAVRTLD PEEADWFFVP VYTTCDLTSS 120 GHPMPFDSPR MMRGAIRLVA ERWPHWNRSE GADHFFVTPH DFGACFHFKE EKAVARGILP 180 LLRRATLVQT FGQRRHACLK GGSITVPPYA PPARMEARRL PPGTPRSVFA YFRGLFYDAG 240 NDPEGGRYAR GARASVWENF RSSPVFDISA ERPATYYEDM QRAVFCLCPL GWAPWSPRLV 300 EAVVFGCIPV VIADGIVLPF ADAIPWADVG VFVAEEDVPR LDTILTSIPP EVVLRKQRLL 360 ASPAVKRAVL FPQPAQPGDA FHQILNGLAR KLPHGDGVFL RPGQTVLNWT AGPPGDLKPW 420 * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-78 | 53 | 348 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACF82849.1 | 0 | 30 | 420 | 27 | 418 | unknown [Zea mays] |
GenBank | ACF86410.1 | 0 | 30 | 420 | 27 | 418 | unknown [Zea mays] |
RefSeq | NP_001045264.1 | 0 | 27 | 420 | 24 | 417 | Os01g0926700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001149319.1 | 0 | 25 | 420 | 26 | 421 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
RefSeq | XP_002441217.1 | 0 | 1 | 420 | 1 | 422 | hypothetical protein SORBIDRAFT_09g022500 [Sorghum bicolor] |