Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00041807m |
Family | GT47 |
Protein Properties | Length: 454 Molecular Weight: 51527.3 Isoelectric Point: 9.3362 |
Chromosome | Chromosome/Scaffold: 016868 Start: 5218 End: 7738 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 41 | 381 | 0 |
RRLRVYVADLPRALNYGLLDRYWSLPAADSRIPASSDPDHPAPHNHPPYPESPLIKQYSAEYWLLASLHTAATAAVRVVADWREADVVFVPFFATLSAEM ELGWGTKGAFRKKDGNEDYRRQREVVDRVTAHPAWRRSGGRDHIFVLTDPVAMWHVRTEIAPAILLVVDFGGWFKLDSKITSRNSPHMIQHTQVSLLKDV IVPYTRLLPTLLLSENKDRPTLLYFKGAKHRHRGGLVREKLWDLLGNEPDIVMEEGFPNATGRDQSIKGMRASEFCLHPAGDTPTSCRLFDAIASLCIPV IVSDEVELPFEGMIDYTEFSIFVSVSNAMKPKWLTNYLKNI |
Full Sequence |
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Protein Sequence Length: 454 Download |
MKRLAVLASS ILLLLLSLSF FLFRPTSRPI LSSLQAFEPD RRLRVYVADL PRALNYGLLD 60 RYWSLPAADS RIPASSDPDH PAPHNHPPYP ESPLIKQYSA EYWLLASLHT AATAAVRVVA 120 DWREADVVFV PFFATLSAEM ELGWGTKGAF RKKDGNEDYR RQREVVDRVT AHPAWRRSGG 180 RDHIFVLTDP VAMWHVRTEI APAILLVVDF GGWFKLDSKI TSRNSPHMIQ HTQVSLLKDV 240 IVPYTRLLPT LLLSENKDRP TLLYFKGAKH RHRGGLVREK LWDLLGNEPD IVMEEGFPNA 300 TGRDQSIKGM RASEFCLHPA GDTPTSCRLF DAIASLCIPV IVSDEVELPF EGMIDYTEFS 360 IFVSVSNAMK PKWLTNYLKN ISKQQKDEFR RNLAHVQPIF EYDTSYSSSR APDGAVNYIW 420 KKIHQKLPMI QEAIIRGKRR PDGTSIPLRC HCT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-60 | 39 | 381 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAE02830.1 | 0 | 24 | 453 | 23 | 464 | OSJNBa0043A12.35 [Oryza sativa (japonica cultivar-group)] |
GenBank | EEC78225.1 | 0 | 24 | 453 | 23 | 452 | hypothetical protein OsI_17865 [Oryza sativa Indica Group] |
RefSeq | NP_001137073.1 | 0 | 24 | 453 | 24 | 458 | hypothetical protein LOC100217246 [Zea mays] |
RefSeq | XP_002448739.1 | 0 | 24 | 453 | 24 | 456 | hypothetical protein SORBIDRAFT_06g032380 [Sorghum bicolor] |
RefSeq | XP_002533317.1 | 0 | 43 | 453 | 55 | 478 | catalytic, putative [Ricinus communis] |