Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00045520m |
Family | GT47 |
Protein Properties | Length: 323 Molecular Weight: 35308.1 Isoelectric Point: 8.5975 |
Chromosome | Chromosome/Scaffold: 0131613 Start: 1 End: 969 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 165 | 314 | 2.2e-28 |
CAGRYIYVQELPNRFNTDLLRGCRSLSEWTDMCKHVANAGMGPRLTRTGGVLPPTGWYDTNQFTLEVVFHNRMRQYVCLTADASRAAAVYVPYYAGLDVG RHLWGFSNDVRDALAEDLVEWLRSTPAWAAHGGRDHFLVGGRIAWDFRRQ |
Full Sequence |
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Protein Sequence Length: 323 Download |
MGSGRAPAAA LRAARWLLPL AVPACCVVWM LLAFAPPTPP ALAVRRREGS QVSGWRIVGT 60 MPGHEDIVHA SPRPPERQET IDTAPAPPES RAAADTSPPP PPERELIVDA SPPPPPKLDE 120 ITGASSPPPN HQARIGIPPS PPPPQVARQE RQSRAATRAA VADRCAGRYI YVQELPNRFN 180 TDLLRGCRSL SEWTDMCKHV ANAGMGPRLT RTGGVLPPTG WYDTNQFTLE VVFHNRMRQY 240 VCLTADASRA AAVYVPYYAG LDVGRHLWGF SNDVRDALAE DLVEWLRSTP AWAAHGGRDH 300 FLVGGRIAWD FRRQDGGEWG SRL |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam10152 | DUF2360 | 0.005 | 59 | 128 | 70 | + Predicted coiled-coil domain-containing protein (DUF2360). This is the conserved 140 amino acid region of a family of proteins conserved from nematodes to humans. One C. elegans member is annotated as a Daf-16-dependent longevity protein 1 but this could not be confirmed. The function is unknown. | ||
pfam03016 | Exostosin | 5.0e-20 | 167 | 309 | 143 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA99677.1 | 0 | 165 | 323 | 97 | 261 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
GenBank | EAY83600.1 | 0 | 165 | 323 | 97 | 261 | hypothetical protein OsI_38822 [Oryza sativa Indica Group] |
RefSeq | XP_002442366.1 | 0 | 3 | 323 | 2 | 332 | hypothetical protein SORBIDRAFT_08g018880 [Sorghum bicolor] |