y
Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00049145m |
Family | GT47 |
Protein Properties | Length: 456 Molecular Weight: 50402.5 Isoelectric Point: 8.9308 |
Chromosome | Chromosome/Scaffold: 072904 Start: 1632 End: 3051 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 80 | 370 | 0 |
GGWYGTNQFALDVIFHNRMKQYECLTNRSVMAAAIFVPFYAGFDFARHHGSAATSKELMVWVTGQPQWAWRMWGRDHFLVAGRTGSDFRRSSNVGPGRGN DLLGMPAARNMSVLVLESTLQHGSDYSVPYPTYFHPRSDAGVLRWQDRVQGQRRTWLMAFVGATRRDTPVSTQVRDHVIAQCKASNACAMLGCARSPGAG SAQCHTHTPATIMRLLQKASFCLQPPGDSWTRRSVFDAMVAGCIPVFFHTASAYKQYRWHLPKDHLSYSVYIPDTDVQQRNVSIEAVLRSI |
Full Sequence |
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Protein Sequence Length: 456 Download |
ARLLAALAVI AWTFFLYLHF PGLSDTVQVS RGNGGADDPC RGRYIFILET TGGGLCASLG 60 NAGLGPPLDD RTDGVFTGEG GWYGTNQFAL DVIFHNRMKQ YECLTNRSVM AAAIFVPFYA 120 GFDFARHHGS AATSKELMVW VTGQPQWAWR MWGRDHFLVA GRTGSDFRRS SNVGPGRGND 180 LLGMPAARNM SVLVLESTLQ HGSDYSVPYP TYFHPRSDAG VLRWQDRVQG QRRTWLMAFV 240 GATRRDTPVS TQVRDHVIAQ CKASNACAML GCARSPGAGS AQCHTHTPAT IMRLLQKASF 300 CLQPPGDSWT RRSVFDAMVA GCIPVFFHTA SAYKQYRWHL PKDHLSYSVY IPDTDVQQRN 360 VSIEAVLRSI PPAMVVRLRE EVIKLIPTVI YADPRSRLET IKDAFDVAVE CILDKVERIK 420 KGEFVGSGRP VSEDPPNLYM STESAFRPKS SVSKE* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-57 | 78 | 370 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_001048943.1 | 0 | 2 | 422 | 46 | 481 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002465869.1 | 0 | 2 | 446 | 53 | 515 | hypothetical protein SORBIDRAFT_01g047310 [Sorghum bicolor] |
RefSeq | XP_002468519.1 | 0 | 2 | 455 | 13 | 485 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
RefSeq | XP_002468520.1 | 0 | 24 | 451 | 39 | 475 | hypothetical protein SORBIDRAFT_01g047300 [Sorghum bicolor] |
RefSeq | XP_002468521.1 | 0 | 24 | 452 | 52 | 503 | hypothetical protein SORBIDRAFT_01g047315 [Sorghum bicolor] |