Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00050116m |
Family | GT47 |
Protein Properties | Length: 387 Molecular Weight: 43578.7 Isoelectric Point: 8.9291 |
Chromosome | Chromosome/Scaffold: 072500 Start: 3422 End: 4582 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 104 | 386 | 0 |
CRGRYVYIHDLPPRFNADIIRNCRKTEDHWADMCRFLRNDGLGRPLADRIDGVIKSEAGWYDTHQFALDAIFHNRMKQYECLTSDSAEASAVFVPFYAGF DFVRYHWGYDNATRDAASVDLTEWLMARPEWRRMGGRDHFLVAGRTGWDFRRSNNVDPDWGNDLLVMPAGQNMSVLVLESAMLHGSDYPVPYPTYFHPRS DADVLRWQDRVRGQRRTWLMAFVGAPRPDVPINIRVRDHVIAQCKASSACTMLGCARATGSTQCHTPGNIMRLFQKTVFCLQP |
Full Sequence |
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Protein Sequence Length: 387 Download |
MERVGAHGGK RWLPRLLLLA ALSWLLMVYL HAAVFHAPAV SAPPHTSLVA VASDREDGRR 60 FLLRQEEQLK KIASASASAS ASALPVAAGE ERRRPRGVGG GDACRGRYVY IHDLPPRFNA 120 DIIRNCRKTE DHWADMCRFL RNDGLGRPLA DRIDGVIKSE AGWYDTHQFA LDAIFHNRMK 180 QYECLTSDSA EASAVFVPFY AGFDFVRYHW GYDNATRDAA SVDLTEWLMA RPEWRRMGGR 240 DHFLVAGRTG WDFRRSNNVD PDWGNDLLVM PAGQNMSVLV LESAMLHGSD YPVPYPTYFH 300 PRSDADVLRW QDRVRGQRRT WLMAFVGAPR PDVPINIRVR DHVIAQCKAS SACTMLGCAR 360 ATGSTQCHTP GNIMRLFQKT VFCLQPP |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-47 | 103 | 387 | 292 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAO17347.1 | 0 | 102 | 387 | 227 | 508 | Hypothetical protein [Oryza sativa Japonica Group] |
GenBank | EEE58313.1 | 0 | 102 | 387 | 261 | 542 | hypothetical protein OsJ_09380 [Oryza sativa Japonica Group] |
RefSeq | NP_001048943.1 | 0 | 101 | 387 | 82 | 364 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002468519.1 | 0 | 100 | 387 | 47 | 334 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
RefSeq | XP_002468520.1 | 0 | 100 | 387 | 52 | 341 | hypothetical protein SORBIDRAFT_01g047300 [Sorghum bicolor] |