Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00054799m |
Family | GT47 |
Protein Properties | Length: 756 Molecular Weight: 85705.3 Isoelectric Point: 6.7012 |
Chromosome | Chromosome/Scaffold: 021275 Start: 785 End: 5162 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 337 | 663 | 0 |
KKRPLIYVYDLPAEFDSHLLEGRHFKFQCVNRIYDDRNRTLWTQQLYGAQMALYESILASPHRTLNGEEADYFYVPVLDSCLITRSDDAPHLLMPRDLRL RSYHALEYYRMAYDHIAQQYPYWNRTSGRDHIWVGFMNSTTAYWADNWDPIPLDRRGNHPCFDPRKDLVLPAWKGPDPGAIWLKLWARPRINRTTLFYFN GNLGPAYEGGRPEDTYSMGIRQKLAAEFGSTPNKQGNLGRQHAADVTVTYLRTEKYYEELASSVFCGVLPGDGWSGRMEDSMLQGCIPVIIQDGIFLPYE NVLNYNSFAVRVQENDIPNLISTLRGI |
Full Sequence |
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Protein Sequence Length: 756 Download |
MLAIRSTKCP VAFVGAASAL VVLVTAVHVF MVPILPSSLD YFRARSSVSD PRNASLGVEV 60 VDSRLREHFP SDSHGAVVFR GAPWKAEIGR WLAGCHANSS SVNITEGIGA KRCEKDCSGR 120 GVCNYDLGEC RCFHGYSGKG CEEVLKLECN LPSSPEWPAG RWIVSMCAAH CDTTRAMCFC 180 GPETKYPDRP VAEACGFKTI LPARPDDPKL TDWKTPDLEN VFTTNRSKSG WCNVVPEDAY 240 SSKVKYKEEC DCKYDGLWGQ FCETHVECSC INQCSGHGHC RGGFCQCDSG YFGIDCSIPS 300 AYSLAYDWPS WLQPRVNLPD MKILSSTPIN VKAIVQKKRP LIYVYDLPAE FDSHLLEGRH 360 FKFQCVNRIY DDRNRTLWTQ QLYGAQMALY ESILASPHRT LNGEEADYFY VPVLDSCLIT 420 RSDDAPHLLM PRDLRLRSYH ALEYYRMAYD HIAQQYPYWN RTSGRDHIWV GFMNSTTAYW 480 ADNWDPIPLD RRGNHPCFDP RKDLVLPAWK GPDPGAIWLK LWARPRINRT TLFYFNGNLG 540 PAYEGGRPED TYSMGIRQKL AAEFGSTPNK QGNLGRQHAA DVTVTYLRTE KYYEELASSV 600 FCGVLPGDGW SGRMEDSMLQ GCIPVIIQDG IFLPYENVLN YNSFAVRVQE NDIPNLISTL 660 RGINETQVEF MLGNVRQMWQ RFFYRDSILL EAQRQKRLFS EEAPWSVEVS KLPDDDDVFA 720 TFIQLLHYKL YNDPWRQGLL QTKETGLPNI CSRAS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00054 | EGF_CA | 0.003 | 267 | 296 | 34 | + Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. | ||
pfam07974 | EGF_2 | 5.0e-5 | 268 | 296 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
pfam03016 | Exostosin | 1.0e-67 | 336 | 663 | 338 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI29877.1 | 0 | 4 | 751 | 33 | 817 | unnamed protein product [Vitis vinifera] |
GenBank | EAZ25771.1 | 0 | 4 | 755 | 1 | 779 | hypothetical protein OsJ_09611 [Oryza sativa Japonica Group] |
GenBank | EEC74609.1 | 0 | 4 | 755 | 1 | 737 | hypothetical protein OsI_10218 [Oryza sativa Indica Group] |
RefSeq | NP_191322.3 | 0 | 1 | 751 | 1 | 788 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002277596.1 | 0 | 4 | 751 | 5 | 789 | PREDICTED: hypothetical protein [Vitis vinifera] |