Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00058137m |
Family | GT47 |
Protein Properties | Length: 509 Molecular Weight: 56400.1 Isoelectric Point: 5.4804 |
Chromosome | Chromosome/Scaffold: 0198027 Start: 302 End: 1973 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 79 | 422 | 0 |
SCEGRYVYMLDLPSRFDMLRDCVAGSPLFDDMWSWCAITVNAGLGPKVVPAAGNGSDGDTGIIPSTGWYSTDQYALEVIFHQWMRRYECLTDDPAAATAV YVPYYPALELHQHLCGFNTTARDGPSEAFLRWLSSQPTWAALGGRDHFMVAAKTTWMFRREPGGGDDGCGNNFLGQPETGNMTVLTYESNIWAPRDIAVP YPSYFHPSSAGEVAAWQARARAAPRPFLFAFAGARRRKGQLAIRDRVFDVCEAAARCGLVDCSHGLEGSITCRTPAKLVSLFTSARFCLQPRGDSFMRRS SIDSVMAGCIPVFFHRASTLAAQYRWHEPGPPGRYYVLLNSDDV |
Full Sequence |
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Protein Sequence Length: 509 Download |
MEAHYPKYLL YCLLIAGSWL ISCLLHLQYL HLSLSSSIAA PRRAALLLPA PAVEADDKLW 60 SASSVAASPS PSSPPPPLSC EGRYVYMLDL PSRFDMLRDC VAGSPLFDDM WSWCAITVNA 120 GLGPKVVPAA GNGSDGDTGI IPSTGWYSTD QYALEVIFHQ WMRRYECLTD DPAAATAVYV 180 PYYPALELHQ HLCGFNTTAR DGPSEAFLRW LSSQPTWAAL GGRDHFMVAA KTTWMFRREP 240 GGGDDGCGNN FLGQPETGNM TVLTYESNIW APRDIAVPYP SYFHPSSAGE VAAWQARARA 300 APRPFLFAFA GARRRKGQLA IRDRVFDVCE AAARCGLVDC SHGLEGSITC RTPAKLVSLF 360 TSARFCLQPR GDSFMRRSSI DSVMAGCIPV FFHRASTLAA QYRWHEPGPP GRYYVLLNSD 420 DVLEGRVDIE EELSRYTDEE VAAMREELIK MMPRFLYRDP RVRFEGEMRD AFDITMDGVM 480 DRMRRIKNGE DVTLKGDDSD EAMGANDS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-35 | 80 | 392 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA96790.1 | 0 | 1 | 508 | 1 | 527 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
DDBJ | BAH95576.1 | 0 | 147 | 508 | 94 | 466 | Os12g0224400 [Oryza sativa Japonica Group] |
GenBank | EEC69035.1 | 0 | 96 | 508 | 1 | 391 | hypothetical protein OsI_37846 [Oryza sativa Indica Group] |
GenBank | EEE52961.1 | 0 | 96 | 508 | 1 | 424 | hypothetical protein OsJ_35605 [Oryza sativa Japonica Group] |
RefSeq | XP_002443053.1 | 0 | 1 | 501 | 1 | 519 | hypothetical protein SORBIDRAFT_08g007160 [Sorghum bicolor] |