| Basic Information | |
|---|---|
| Species | Panicum virgatum |
| Cazyme ID | Pavirv00060828m |
| Family | AA3 |
| Protein Properties | Length: 597 Molecular Weight: 63591.5 Isoelectric Point: 8.6012 |
| Chromosome | Chromosome/Scaffold: 015398 Start: 752 End: 2917 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 49 | 587 | 0 |
| AYYDYIIIGGGTAGCPLAATLSQRSRVLLLERGGSPYEDGRVLSMLHFSDVLADTSASSPSQRFVSEDGVINSRPRVLGGGSCINAGFFTRAGAGYVRAA GWDPREVLAAYRWVEDVVAFQPALGPWQAAVRRGLLETGVLPDNGVTYDHIPGTKVGGSIFDADGRRHTAADLLRYSNPDGIDLFLRARVARILFGYKGT KPVARGVVYRDAQGGTHVAYLNRGGANEVILSAGALGSPQQLMLSGIGPADHLRSLGIDVILDLPGVGQGMSDNPMNAIYVPSPSPVEVSLIQVVGITRF GSYIEGASGANWNSHPSGTQPPPPRNFGMFSPQTGQLATVPPAQRTPEAIARAVEAMSQVPDAALRGGFILEKVLGPQSTGSLALRNLDPDDNPSVRFNY FAHPDDLRRCVAGISAIERVIRSRAFSRFTYPNFAFPAALNVTADFPVNTLYGGRRFGGGGGGGDPRALEQFCRDTVMTIWHYHGGCQVGRVVDRDYKVL GVEALRVIDGSTFNASPGTNPQATVMMLGRYMGVKLLKE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 597 Download |
| MAPVLISAQA MPVFTVACFF ALLCMAQQVR AVSVNYTFMR EAVNAPPVAY YDYIIIGGGT 60 AGCPLAATLS QRSRVLLLER GGSPYEDGRV LSMLHFSDVL ADTSASSPSQ RFVSEDGVIN 120 SRPRVLGGGS CINAGFFTRA GAGYVRAAGW DPREVLAAYR WVEDVVAFQP ALGPWQAAVR 180 RGLLETGVLP DNGVTYDHIP GTKVGGSIFD ADGRRHTAAD LLRYSNPDGI DLFLRARVAR 240 ILFGYKGTKP VARGVVYRDA QGGTHVAYLN RGGANEVILS AGALGSPQQL MLSGIGPADH 300 LRSLGIDVIL DLPGVGQGMS DNPMNAIYVP SPSPVEVSLI QVVGITRFGS YIEGASGANW 360 NSHPSGTQPP PPRNFGMFSP QTGQLATVPP AQRTPEAIAR AVEAMSQVPD AALRGGFILE 420 KVLGPQSTGS LALRNLDPDD NPSVRFNYFA HPDDLRRCVA GISAIERVIR SRAFSRFTYP 480 NFAFPAALNV TADFPVNTLY GGRRFGGGGG GGDPRALEQF CRDTVMTIWH YHGGCQVGRV 540 VDRDYKVLGV EALRVIDGST FNASPGTNPQ ATVMMLGRYM GVKLLKERML VEGPGA* 600 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| PRK02106 | PRK02106 | 1.0e-13 | 425 | 577 | 157 | + choline dehydrogenase; Validated |
| PRK02106 | PRK02106 | 3.0e-33 | 51 | 321 | 321 | + choline dehydrogenase; Validated |
| TIGR01810 | betA | 6.0e-36 | 52 | 577 | 568 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
| COG2303 | BetA | 3.0e-47 | 51 | 590 | 586 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
| PLN02785 | PLN02785 | 0 | 51 | 589 | 540 | + Protein HOTHEAD |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009055 | electron carrier activity |
| GO:0016491 | oxidoreductase activity |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACN31684.1 | 0 | 13 | 593 | 4 | 576 | unknown [Zea mays] |
| DDBJ | BAD29242.1 | 0 | 22 | 595 | 16 | 619 | putative mandelonitrile lyase [Oryza sativa Japonica Group] |
| GenBank | EAY87068.1 | 0 | 22 | 595 | 16 | 580 | hypothetical protein OsI_08464 [Oryza sativa Indica Group] |
| RefSeq | NP_001149739.1 | 0 | 13 | 593 | 4 | 576 | protein HOTHEAD [Zea mays] |
| RefSeq | XP_002454481.1 | 0 | 1 | 592 | 1 | 583 | hypothetical protein SORBIDRAFT_04g031910 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 37 | 588 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 37 | 588 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 37 | 588 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 37 | 588 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 37 | 588 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
| cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
| suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
